Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,262 questions · 2,405 findings · 248 reviews · Headline outcomes only

No studies found 507 · 21.1%GRADE not reported 93 · 3.9%Very low 657 · 27.3%Low 708 · 29.4%Moderate 387 · 16.1%High 53 · 2.2%

Care delivery and self‐management strategies vs usual care

Seizure frequency and seizure severity · children/adolescents with epilepsy and/or their parents

Care delivery and self‐management strategies showed no clear difference in seizure severity (frequency and duration of seizures) at 3 months compared with usual care (low certainty).

1 finding from 1 review

Care delivery and self‐management strategies vs usual care

Epilepsy Knowledge Test for Children (EKTC) at 3 months · children/adolescents with epilepsy and/or their parents

Care delivery and self‐management strategies showed no clear difference in epilepsy Knowledge Test for Children (EKTC) at 3 months compared with usual care (moderate certainty).

1 finding from 1 review

Care delivery and self‐management strategies vs usual care

Self‐perception of epilepsy on quality of life (PedsQL) at 3 months · children/adolescents with epilepsy and/or their parents

Care delivery and self‐management strategies showed no clear difference in self‐perception of epilepsy on quality of life (PedsQL) at 3 months compared with usual care (low certainty).

1 finding from 1 review

Primary health professional‐led or collaborative care vs usual or enhanced care

Depressive symptoms · women with perinatal depression

It is very uncertain whether primary health professional‐led collaborative care interventions changes depression symptoms ‐ intermediate term (1 to 6 months post… compared with usual or enhanced care (very low certainty).

1 finding from 1 review

Primary health professional‐led or collaborative care vs usual or enhanced care

Quality of life ‐ intermediate term (1 to 6 months post intervention) SF‐36 social functioning (higher score = higher quality of life) · women with perinatal depression

It is very uncertain whether primary health professional‐led collaborative care interventions changes quality of life ‐ intermediate term (1 to 6 months post… compared with usual or enhanced care (very low certainty).

1 finding from 1 review