Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

331 questions · 353 findings · 56 reviews

No studies found 41 · 11.6%GRADE not reported 74 · 21%Very low 128 · 36.3%Low 66 · 18.7%Moderate 32 · 9.1%High 12 · 3.4%

Intervention not reported

In‐hospital mortality · mechanically ventilated adults with acute respiratory distress syndrome. Participants were recruited from ICUs internationally, including…

The intervention showed no clear difference in in‐hospital mortality (low certainty).

1 finding from 1 review

Intervention not reported

Rate of barotrauma · mechanically ventilated adults with acute respiratory distress syndrome. Participants were recruited from ICUs internationally, including…

The intervention showed no clear difference in rate of barotrauma (moderate certainty).

1 finding from 1 review

Aesthetic (resin-veneered) crowns vs Conventional metal (stainless steel) crowns

Restoration failure · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic or symptom free

Aesthetic (resin-veneered) crowns showed no clear difference in restoration failure at 6 months compared with conventional metal (stainless steel) crowns; GRADE not reported.

1 finding from 1 review

Aesthetic (resin-veneered) crowns vs Conventional metal (stainless steel) crowns

Occlusion · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic or symptom free

Aesthetic (resin-veneered) crowns led to lower occlusion at 6 months compared with conventional metal (stainless steel) crowns; GRADE not reported.

1 finding from 1 review

Aesthetic (resin-veneered) crowns vs Conventional metal (stainless steel) crowns

Proximal contact at 6 months · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic or symptom free

Aesthetic (resin-veneered) crowns led to lower proximal contact at 6 months compared with conventional metal (stainless steel) crowns; GRADE not reported.

1 finding from 1 review

Aesthetic (resin-veneered) crowns vs Conventional metal (stainless steel) crowns

Marginal integrity of restoration · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic or symptom free

Aesthetic (resin-veneered) crowns led to lower marginal integrity at 6 months compared with conventional metal (stainless steel) crowns; GRADE not reported.

1 finding from 1 review

Aesthetic (resin-veneered) crowns vs Conventional metal (stainless steel) crowns

Gingival health at 6 months · Children aged 12 years or younger with tooth decay involving at least one tooth in the primary dentition, symptomatic or symptom free

Aesthetic (resin-veneered) crowns showed no clear difference in gingival health at 6 months compared with conventional metal (stainless steel) crowns; GRADE not reported.

1 finding from 1 review

Intervention not reported

Change in pain Visual Analog Scale (VAS) at 12 weeks (0 to 10 scale; lower score means less pain) · people with rheumatoid arthritis

It is very uncertain whether the intervention changes change in pain Visual Analog Scale (VAS) at 12 weeks (0 to 10 scale;… (very low certainty).

1 finding from 1 review

Intervention not reported

Change in measure of disease activity Disease Activity Score (DAS‐28‐ESR) at 12 weeks (0 to 10 score; lower score means less disease activity) · people with rheumatoid arthritis

It is very uncertain whether the intervention changes change in measure of disease activity Disease Activity Score… (very low certainty).

1 finding from 1 review

Intervention not reported

Change in function Health Assessment Questionnaire (HAQ) at 12 weeks (0 to 3 score; lower score means better function) · people with rheumatoid arthritis

It is very uncertain whether the intervention changes change in function Health Assessment Questionnaire (HAQ) at 12 weeks… (very low certainty).

1 finding from 1 review