Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

884 questions · 892 findings · 68 reviews · Anaesthesia

No studies found 118 · 13.2%GRADE not reported 156 · 17.5%Very low 187 · 21%Low 270 · 30.3%Moderate 119 · 13.3%High 42 · 4.7%

Intervention not reported

Intraoperative Wakefulness Postoperative Interview · patients with prevention of recall of events during surgery

The intervention may leads to lower intraoperative Wakefulness Postoperative Interview (low certainty).

1 finding from 1 review

Intervention not reported

Adverse effects of intraoperative wakefulness and/or postoperative awareness (i.e. post‐traumatic stress syndrome, myocardial infarction, cardiac arrest, etc.) · patients with prevention of recall of events during surgery

The review found no eligible studies for this question.

1 finding from 1 review

Thiopentone and ketamine vs benzodiazepines

Awareness Postoperative interview · patients with prevention of recall of events during surgery

It is very uncertain whether thiopentone and ketamine changes awareness Postoperative interview compared with benzodiazepines (diazepam, midazolam, lorazepam) (very low certainty).

1 finding from 1 review

Thiopentone and ketamine vs benzodiazepines

Adverse effects of intraoperative wakefulness and/or postoperative awareness (i.e. post‐traumatic stress syndrome, myocardial infarction, cardiac arrest, etc.) · patients with prevention of recall of events during surgery

The review found no eligible studies for this question.

1 finding from 1 review

Propofol vs sevoflurane

Adverse event ‐ haemodynamic changes, number of events · patients with rapid emergence from anaesthesia after undergoing brain tumour surgery

Propofol may leads to higher adverse event ‐ haemodynamic changes, number of events compared with sevoflurane (low certainty).

1 finding from 1 review

Propofol vs sevoflurane

Adverse event ‐ pain, visual analogue scale · patients with rapid emergence from anaesthesia after undergoing brain tumour surgery

Propofol showed no clear difference in adverse event ‐ pain, visual analogue scale compared with sevoflurane (low certainty).

1 finding from 1 review