Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,288 questions · 3,354 findings · 516 reviews · Headline outcomes only

No studies found 720 · 21.5%GRADE not reported 164 · 4.9%Very low 950 · 28.3%Low 932 · 27.8%Moderate 434 · 12.9%High 154 · 4.6%

Inhaled NO vs placebo

Frequency of pain crises in the · people with SCD

Inhaled nitric oxide showed no clear difference in frequency of pain crises in the compared with placebo (low certainty).

2 findings from 1 review

Inhaled NO vs placebo or conventional therapy

Mortality before hospital discharge · all infants and children with congenital heart disease having postoperative management of pulmonary hypertension

It is very uncertain whether inhaled nitric oxide changes mortality prior to discharge1 compared with placebo or conventional therapy (very low certainty).

1 finding from 1 review

Electrical stimulation vs No active treatment (control)

Cure: number of women with self‐reported continence · women with stress urinary incontinence

Electrical stimulation probably leads to higher cure: number of women with self‐reported continence compared with no active treatment (moderate certainty).

1 finding from 1 review