Findings

What do systematic reviews say?

539 questions · 553 findings · 58 reviews · Airways

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No studies found 37 · 6.7%GRADE not reported 8 · 1.4%Very low 27 · 4.9%Low 161 · 29.1%Moderate 219 · 39.6%High 101 · 18.3%

Selexipag vs placebo

mPAP (the higher the mPAP, the worse the pulmonary hypertension) · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Moderate

Selexipag vs placebo

PVR · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Moderate

Selexipag vs placebo

Cardiac index · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Moderate

Selexipag vs placebo

RAP · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Moderate

Selexipag vs placebo

Dyspnea · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Moderate

Selexipag vs placebo

Headache+ · pulmonary arterial hypertension

1 finding from 1 review

Prostacyclin for pulmonary arterial hypertension 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 1199 participants
High

Inhaled corticosteroids vs placebo

Lung function: FEV1 mL (change from baseline) · people with bronchiectasis

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 156 participants
Low

Inhaled corticosteroids vs placebo

Number of participants improved · people with bronchiectasis

Inhaled corticosteroids showed no clear difference in number of participants improved compared with placebo (low certainty).

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
OR 0.57 [0.24, 1.34]
1 study · 86 participants
Low

Inhaled corticosteroids vs placebo

Lung function (spirometry indices) ‐ FVC (in L, end study minus baseline values) · people with bronchiectasis

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 156 participants
Low

Inhaled corticosteroids vs placebo

Lung function (other indices) ‐ diffusion capacity % predicted (end of study) · people with bronchiectasis

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 57 participants
Low

Inhaled corticosteroids vs placebo

Lung function (other indices) ‐ RV % predicted (end of study values) · people with bronchiectasis

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 57 participants
Low

Inhaled corticosteroids vs placebo

Lung function (other indices) ‐ TLC % predicted (end of study values) · people with bronchiectasis

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 57 participants
Low

Inhaled corticosteroids vs placebo

Exacerbations · people with bronchiectasis

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 127 participants
Low

Inhaled corticosteroids vs placebo

Pseudomonas aeruginosa (P aeruginosa) colonisation · people with bronchiectasis

Inhaled corticosteroids showed no clear difference in pseudomonas aeruginosa (P aeruginosa) colonisation compared with placebo (low certainty).

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
OR 0.94 [0.45, 1.96]
2 studies · 156 participants
Low

Inhaled corticosteroids vs placebo

FEV1 % predicted: absolute change from baseline · people with bronchiectasis

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 86 participants
Low

Inhaled corticosteroids vs placebo

FVC (% predicted) Change from baseline · people with bronchiectasis

1 finding from 1 review

Inhaled corticosteroids for bronchiectasis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 86 participants
Low

Influenza vaccine vs placebo

Total exacerbations per participant · COPD

1 finding from 1 review

Influenza vaccine for chronic obstructive pulmonary disease (COPD) 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 180 participants
Low

Influenza vaccine vs placebo

Early exacerbations per participant · COPD

1 finding from 1 review

Influenza vaccine for chronic obstructive pulmonary disease (COPD) 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 180 participants
Low

Influenza vaccine vs placebo

Late exacerbations per participant · COPD

1 finding from 1 review

Influenza vaccine for chronic obstructive pulmonary disease (COPD) 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 180 participants
Low

Influenza vaccine vs placebo

Days disability from respiratory illness · COPD

The review found no eligible studies for this question.

1 finding from 1 review

Influenza vaccine for chronic obstructive pulmonary disease (COPD) 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found