Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

778 questions · 809 findings · 116 reviews

No studies found 205 · 25.3%GRADE not reported 111 · 13.7%Very low 225 · 27.8%Low 155 · 19.2%Moderate 85 · 10.5%High 28 · 3.5%

Radiotherapy vs botulinum toxin

Reduction in the amount of saliva production in the short term using an objective measure · sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis

The review found no eligible studies for this question.

1 finding from 1 review

Radiotherapy vs botulinum toxin

Adverse events, reported as "negative experiences" · sialorrhea (excessive saliva) in people with motor neuron disease/amyotrophic lateral sclerosis

It is very uncertain whether radiotherapy changes adverse events, reported as "negative experiences" compared with botulinum toxin (very low certainty).

1 finding from 1 review

ISBCS vs DSBCS

Proportion of participants with endophthalmitis · people with bilateral age‐related cataracts (NRSs)
2 findings from 1 review

ISBCS vs DSBCS

Complications · people with bilateral age‐related cataracts (NRSs)

It is very uncertain whether ISBCS changes complications compared with DSBCS (very low certainty).

2 findings from 1 review

ISBCS vs DSBCS

Total costs per QALY · people with bilateral age‐related cataracts (NRSs)

The review found no eligible studies for this question.

2 findings from 1 review

ISBCS vs DSBCS

BCDVA · people with bilateral age‐related cataracts (NRSs)

The review found no eligible studies for this question.

2 findings from 1 review

ISBCS vs DSBCS

Patient‐reported outcome measures (PROMs) · people with bilateral age‐related cataracts (NRSs)

The review found no eligible studies for this question.

2 findings from 1 review

ISBCS vs DSBCS

Refraction NOT within 1.0 dioptres of target · people with bilateral age‐related cataracts (NRSs)

ISBCS showed no clear difference in refraction NOT within 1.0 dioptres of target compared with DSBCS (moderate certainty).

2 findings from 1 review

Autologous blood or PRP vs placebo at 3 months' follow‐up

Treatment success (> 25% improvement in pain or function) · lateral elbow pain

It is very uncertain whether autologous blood or PRP changes treatment success (> 25% improvement in pain or function) compared with placebo at 3 months' follow‐up (very low certainty).

1 finding from 1 review