Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

332 questions · 335 findings · 55 reviews · Headline outcomes only

No studies found 77 · 23%GRADE not reported 3 · 0.9%Very low 113 · 33.7%Low 75 · 22.4%Moderate 61 · 18.2%High 6 · 1.8%

Cyanoacrylate vs alcohol

Re‐bleeding Re‐bleeding after intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes re‐bleeding Re‐bleeding after intervention compared with alcohol (very low certainty).

1 finding from 1 review

Cyanoacrylate vs alcohol

Control of bleeding Success in control the active variceal bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes control of bleeding Success in controlling the active variceal… compared with alcohol (very low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Failure of intervention Continuous variceal bleeding after intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes failure of intervention Continuous variceal bleeding after… compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Re‐bleeding Re‐bleeding after the bleeding was controlled in the first intervention · acute bleeding gastric varices in people with portal hypertension

Cyanoacrylate may leads to lower re‐bleeding Re‐bleeding after the bleeding was controlled in the… compared with band ligation (low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Complications (general) Number of total complications · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes complications (general) Number of total complications compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate vs band ligation

Control of bleeding Success in control the active variceal bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate changes control of bleeding Success in control variceal bleeding compared with band ligation (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Total mortality Total deaths and the end of · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes total mortality Total deaths and the end of compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

day ‐ mortality Mortality due to bleeding · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes day ‐ mortality Mortality due to bleeding compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Failure of intervention Continuous bleeding after intervention · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes failure of intervention Continuous bleeding after intervention compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Cyanoacrylate 1 mL vs cyanoacrylate 0.5 mL

Complications (fever) Presence of fever · acute bleeding gastric varices in people with portal hypertension

It is very uncertain whether cyanoacrylate 1 mL changes complications (fever) Presence of fever compared with cyanoacrylate 0.5 mL (very low certainty).

1 finding from 1 review

Open surgery vs ERCP

Retained stones after primary intervention · with common bile duct stones

Open surgery probably leads to lower retained stones after primary intervention compared with ERCP (moderate certainty).

1 finding from 1 review