Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

311 questions · 316 findings · 105 reviews · Schizophrenia

No studies found 14 · 4.4%GRADE not reported 11 · 3.5%Very low 143 · 45.3%Low 79 · 25%Moderate 66 · 20.9%High 3 · 0.9%

HIGH DOSE (greater than or equal to 10 mg/day) vs ANY DOSE ‐ short term

Leaving the study early: insufficient response ‐ When compared with standard‐lower dose (greater than or equal to 4‐<6 mg/day) · patients with schizophrenia

HIGH DOSE (greater than or equal to 10 mg/day) showed no clear difference in leaving the study early: insufficient response ‐ When compared with… compared with ANY DOSE ‐ short term (moderate certainty).

1 finding from 1 review

HIGH DOSE (greater than or equal to 10 mg/day) vs ANY DOSE ‐ short term

Leaving the study early: insufficient response ‐ When compared with standard‐higher dose (greater than or equal to 6‐<10 mg/day) · patients with schizophrenia

HIGH DOSE (greater than or equal to 10 mg/day) showed no clear difference in leaving the study early: insufficient response ‐ When compared with… compared with ANY DOSE ‐ short term (moderate certainty).

1 finding from 1 review

LOW DOSE (greater than or equal to 2‐<4 mg/day) vs ANY DOSE ‐ short term

Leaving the study early · patients with schizophrenia

LOW DOSE (greater than or equal to 2‐<4 mg/day) showed no clear difference in leaving the study early: any reason ‐ when compared with… compared with ANY DOSE ‐ short term (moderate certainty).

2 findings from 1 review

PHASE SPECIFIC TREATMENT (RISPERIDONE + CBT) + SPECIALISED TEAM vs SPECIALISED TEAM

Progression to psychosis ‐ by 12 months · people with psychosis

PHASE SPECIFIC TREATMENT (RISPERIDONE + CBT) + SPECIALISED TEAM probably leads to lower progression to psychosis ‐ by 6 months compared with SPECIALISED TEAM (moderate certainty).

2 findings from 1 review

SPECIALISED TEAM vs usual care

Compliance with treatment ‐ treatment stopped in spite of need ‐ by one year · people with psychosis

SPECIALISED TEAM probably leads to lower compliance with treatment ‐ treatment stopped in spite of need ‐ by… compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

SPECIALISED TEAM vs usual care

Compliance with treatment ‐ treatment stopped in spite of need ‐ by two years · people with psychosis

SPECIALISED TEAM showed no clear difference in compliance with treatment ‐ treatment stopped in spite of need ‐ by… compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

SPECIALISED TEAM vs usual care

Service use: 2. Not hospitalised ‐ by five years · people with psychosis

SPECIALISED TEAM showed no clear difference in service use: 2. Not hospitalised ‐ by five years compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

SPECIALISED TEAM vs usual care

Social outcomes: 1. Not living independently ‐ by 5 years · people with psychosis

SPECIALISED TEAM probably leads to lower social outcomes: 1. Not living independently ‐ by 5 years compared with STANDARD CARE (moderate certainty).

1 finding from 1 review

SPECIALISED TEAM vs usual care

Social outcomes: 2. Not working or in education ‐ by 5 years · people with psychosis

SPECIALISED TEAM showed no clear difference in social outcomes: 2. Not working or in education ‐ by 5 years compared with STANDARD CARE (moderate certainty).

1 finding from 1 review