Findings

What do systematic reviews say?

1,352 questions · 1,400 findings · 169 reviews

Sort:Best matchNewest Highest certainty Download CSV

No studies found 309 · 22.1%GRADE not reported 115 · 8.2%Very low 350 · 25%Low 324 · 23.1%Moderate 240 · 17.1%High 62 · 4.4%

Summary of findings: Inhaled antibiotics vs IV antibiotics

Time to next pulmonary exacerbation · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

1 finding from 1 review

Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Very low

Summary of findings: Inhaled antibiotics vs IV antibiotics

Adverse events · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

1 finding from 1 review

Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Very low

Summary of findings: Inhaled antibiotics vs IV antibiotics

Microbiology Emergence of resistant organisms · adults and children with cystic fibrosis (during acute exacerbations of lung disease)

1 finding from 1 review

Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
Very low

Antibiotics (systemic) vs No antibiotics, placebo, or a different type of antibiotic

Outcome not reported · Patients (mainly children and young adults) with a history of dental trauma and a diagnosis of luxation (intrusion, extrusion, or lateral…

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for treating traumatised permanent front teeth: luxated (dislodged) teeth 2013 · Cochrane All outcomes
Minimum 12 months follow-up
Types of antibiotics: the effect of using no antibiotics, a placebo or different types of antibiotics. Main results: No randomised or quasi-randomised controlled trials were found; no study was included in this review.
0 studies
No studies found

Summary of findings table ‐ Delayed antibiotics vs immediate antibiotics

Clinical outcomes · respiratory infections

1 finding from 1 review

Immediate versus delayed versus no antibiotics for respiratory infections 2023 · Cochrane Headline outcomes only
no estimate extracted
11 studies · 2748 participants
Moderate

Summary of findings table ‐ Delayed antibiotics vs immediate antibiotics

Duration of clinical outcomes (pain, malaise, fever) · respiratory infections

1 finding from 1 review

Immediate versus delayed versus no antibiotics for respiratory infections 2023 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 1077 participants
Moderate

Summary of findings table ‐ Delayed antibiotics vs no antibiotics

Clinical outcomes: pain, malaise, fever · respiratory infections

1 finding from 1 review

Immediate versus delayed versus no antibiotics for respiratory infections 2023 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 1685 participants
Moderate

Summary of findings table ‐ Delayed antibiotics vs no antibiotics

Duration of clinical outcomes (pain, malaise, fever) · respiratory infections

1 finding from 1 review

Immediate versus delayed versus no antibiotics for respiratory infections 2023 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 585 participants
Moderate

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Prosthesis failure · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in prosthesis failure compared with no antibiotics or placebo; GRADE not reported.

1 finding from 1 review

Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications 2013 · Cochrane All outcomes
3 to 5 months
RR 0.44 [0.19, 1.00]
5 studies · 1107 participants
GRADE not reported

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Postoperative infection · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in postoperative infection compared with no antibiotics or placebo; GRADE not reported.

1 finding from 1 review

Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications 2013 · Cochrane All outcomes
3 to 5 months
RR 0.69 [0.36, 1.35]
6 studies · 1162 participants
GRADE not reported

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Implant failure · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) probably leads to lower implant failure compared with no antibiotics or placebo (moderate certainty).

1 finding from 1 review

Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications 2013 · Cochrane All outcomes
4 months
RR 0.33 [0.16, 0.67]
6 studies · 1162 participants
Moderate

Prophylactic systemic antibiotics (amoxicillin) vs placebo or no antibiotic

Adverse events · Adults undergoing dental implant placement

Prophylactic systemic antibiotics (amoxicillin) showed no clear difference in adverse events compared with no antibiotics or placebo; GRADE not reported.

1 finding from 1 review

Interventions for replacing missing teeth: antibiotics at dental implant placement to prevent complications 2013 · Cochrane All outcomes
3 to 5 months
RR 1.0 [0.06, 15.85]
6 studies · 1162 participants
GRADE not reported

Antibiotics on removal of central venous catheter vs no antibiotics

Late‐onset blood steam infection · newborn infants undergoing removal of central venous catheter

Antibiotics on removal of central venous catheter showed no clear difference in late‐onset blood steam infection compared with no antibiotics (low certainty).

1 finding from 1 review

Antibiotics at the time of removal of central venous catheter to reduce morbidity and mortality in newborn infants 2018 · Cochrane Headline outcomes only
RR 0.09 [0.01, 1.6]
1 study · 88 participants
Low

Antibiotics on removal of central venous catheter vs no antibiotics

Neonatal mortality · newborn infants undergoing removal of central venous catheter

1 finding from 1 review

Antibiotics at the time of removal of central venous catheter to reduce morbidity and mortality in newborn infants 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 88 participants
Low

Antibiotics on removal of central venous catheter vs no antibiotics

Mortality before hospital discharge · newborn infants undergoing removal of central venous catheter

1 finding from 1 review

Antibiotics at the time of removal of central venous catheter to reduce morbidity and mortality in newborn infants 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 88 participants
Low

Antibiotics on removal of central venous catheter vs no antibiotics

Infection‐related mortality before hospital discharge · newborn infants undergoing removal of central venous catheter

1 finding from 1 review

Antibiotics at the time of removal of central venous catheter to reduce morbidity and mortality in newborn infants 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 88 participants
Low

Antibiotics on removal of central venous catheter vs no antibiotics

Central line‐associated blood stream infection · newborn infants undergoing removal of central venous catheter

Antibiotics on removal of central venous catheter showed no clear difference in central line‐associated blood stream infection compared with no antibiotics (low certainty).

1 finding from 1 review

Antibiotics at the time of removal of central venous catheter to reduce morbidity and mortality in newborn infants 2018 · Cochrane Headline outcomes only
RR 0.09 [0.01, 1.6]
1 study · 88 participants
Low

Topical antibiotics vs placebo/no treatment

Resolution of ear discharge ‐ measured at 1 to 2 weeks · patients with mucopurulent otorrhoea

It is very uncertain whether topical antibiotics changes resolution of ear discharge ‐ measured at 1 to 2 weeks compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
RR 6.74 [1.82, 24.99]
1 study · 35 participants
Very low

Topical antibiotics vs placebo/no treatment

Resolution of ear discharge ‐ measured after 4 weeks · patients with mucopurulent otorrhoea

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Topical antibiotics vs placebo/no treatment

Health‐related quality of life · patients with mucopurulent otorrhoea

The review found no eligible studies for this question.

1 finding from 1 review

Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found