Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,805 questions · 2,912 findings · 307 reviews · Headline outcomes only

No studies found 706 · 24.2%GRADE not reported 133 · 4.6%Very low 786 · 27%Low 696 · 23.9%Moderate 474 · 16.3%High 117 · 4%

Mosaicplasty vs microfracture

Activity · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes activity: intermediate term (1 to 5 years compared with microfracture (very low certainty).

1 finding from 1 review

Mosaicplasty vs microfracture

Activity: long term (5 or more years · Adults with isolated cartilage defects (defect areas 1.0 cm2 to 6.0 cm2) of the knee

It is very uncertain whether mosaicplasty changes activity: long term (5 or more years compared with microfracture (very low certainty).

1 finding from 1 review

LHWs vs usual care

Mortality among children less than 5 years Verbal autopsy · patients with reducing mortality and morbidity in children <5 years

LHWs showed no clear difference in mortality among children less than 5 years Verbal autopsy compared with usual care (low certainty).

1 finding from 1 review