Findings

What do systematic reviews say?

4,749 questions · 17,858 findings · 1,266 reviews

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No studies found 4,359 · 24.4%GRADE not reported 2,348 · 13.1%Very low 4,634 · 25.9%Low 4,000 · 22.4%Moderate 2,052 · 11.5%High 465 · 2.6%

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Antiplatelet agent vs placebo

Adverse events (not reported) · asymptomatic carotid stenosis

Antiplatelet agent showed no clear difference in adverse events (not reported) compared with placebo (low certainty).

1 finding from 1 review

Pharmacological interventions for asymptomatic carotid stenosis 2023 · Cochrane Headline outcomes only
RR 0.81 [0.41, 1.59]
1 study · 372 participants
Low

Antiplatelet agent vs placebo

Quality of life · asymptomatic carotid stenosis

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for asymptomatic carotid stenosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antihypertensive agent vs placebo

Outcomes (measurement/time point) · asymptomatic carotid stenosis

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for asymptomatic carotid stenosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Peak IL‐6 (between the end of surgery and 24 hours post‐surgery)

1 finding from 1 review

Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
152 studies · 6485 participants
Very low

Intervention not reported

Peak IL‐8 (between the end of surgery and 6 hours post‐surgery)

1 finding from 1 review

Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
72 studies · 2963 participants
Very low

Intervention not reported

Hospital or 30‐day mortality

It is very uncertain whether the intervention changes hospital or 30‐day mortality (very low certainty).

1 finding from 1 review

Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults 2023 · Cochrane Headline outcomes only
RR 0.78 [0.68, 0.91]
190 studies · 24817 participants
Very low

Intervention not reported

Myocardial injury (hospital stay)

It is very uncertain whether the intervention changes myocardial injury (hospital stay) (very low certainty).

1 finding from 1 review

Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults 2023 · Cochrane Headline outcomes only
RR 1.04 [0.95, 1.14]
86 studies · 23118 participants
Very low

Intervention not reported

Kidney injury (safety outcome) (hospital stay)

The intervention showed no clear difference in kidney injury (safety outcome) (hospital stay) (low certainty).

1 finding from 1 review

Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults 2023 · Cochrane Headline outcomes only
RR 1.06 [0.96, 1.16]
79 studies · 23103 participants
Low

Intervention not reported

Surgical Site Infection (hospital stay)

The intervention showed no clear difference in surgical Site Infection (hospital stay) (low certainty).

1 finding from 1 review

Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults 2023 · Cochrane Headline outcomes only
RR 0.92 [0.83, 1.01]
40 studies · 19368 participants
Low

Intervention not reported

Duration of hospital length of stay

1 finding from 1 review

Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults 2023 · Cochrane Headline outcomes only
no estimate extracted
148 studies · 15547 participants
Very low

Intervention not reported

Adherence to treatment (number of participants undertaking physical activity) · people with CF

It is very uncertain whether the intervention changes adherence to treatment (number of participants undertaking physical… (very low certainty).

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
RR 3.67 [1.24, 10.85]
1 study · 34 participants
Very low

Intervention not reported

Frequency of hospitalisation for respiratory infection · people with CF

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Frequency of non‐hospitalised respiratory infection · people with CF

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

FEV1 % predicted (change from baseline) · people with CF

It is very uncertain whether the intervention changes FEV1 % predicted (change from baseline) (very low certainty).

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

Intervention not reported

FVC % predicted (change from baseline) · people with CF

It is very uncertain whether the intervention changes FVC % predicted (change from baseline) (very low certainty).

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

Intervention not reported

QoL (change from baseline) · people with CF

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

Intervention not reported

Exercise capacity (change from baseline) VO2 peak · people with CF

It is very uncertain whether the intervention changes exercise capacity (change from baseline) VO2 peak (very low certainty).

1 finding from 1 review

Interventions for improving adherence to airway clearance treatment and exercise in people with cystic fibrosis 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 34 participants
Very low

Motor imaging vs usual care

Prosthesis use · people with transtibial amputation due to peripheral arterial disease or diabetes

1 finding from 1 review

Interventions for motor rehabilitation in people with transtibial amputation due to peripheral arterial disease or… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 8 participants
GRADE not reported

Gait training protocol focused on impairment level vs gait training protocol focused on task level

Quality of life · people with transtibial amputation due to peripheral arterial disease or diabetes

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for motor rehabilitation in people with transtibial amputation due to peripheral arterial disease or… 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Gait training protocol focused on impairment level vs gait training protocol focused on task level

Mobility · people with transtibial amputation due to peripheral arterial disease or diabetes

1 finding from 1 review

Interventions for motor rehabilitation in people with transtibial amputation due to peripheral arterial disease or… 2023 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
Very low