Improvement of histological features (not improved) · People with a diagnosis of oral leukoplakia
1 finding from 1 review
SoF 6, Histological changes: 'Not measured'. Effects text: data on histological changes from Armstrong 2013 were not available for analysis, but study authors reported no statistically significant differences in…
1 study
GRADE not reported
Adverse events: Clinically important specific adverse events · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…
The review found no eligible studies for this question.
1 finding from 1 review
Adverse effects (narrative) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomesshort-term (up to 3 months)
SoF4. Adverse effects: single study narratively reported 4 participants (20%) in the bethanechol arm experienced adverse events (nausea, dizziness, blood pressure fall, cold perspiration or sporadic abdominal pain);…
1 study · 40 participants
Very low
Adverse effects of pain treatment · Adults undergoing orthodontic treatment
The review found no eligible studies for this question.
1 finding from 1 review
Adverse events · Children and adolescents having orthodontic separator placement (without local anaesthetic)
1 finding from 1 review
Tiredness · Children with obstructive sleep apnoea (aged 15 years or younger)
It is very uncertain whether oral appliance or functional orthopaedic appliance changes daytime symptom: tiredness (Brouillette questionnaire) compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Nocturnal symptom: habitual snoring (questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)
It is very uncertain whether oral appliance or functional orthopaedic appliance changes nocturnal symptom: habitual snoring (questionnaire) compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Pain measured by valid instruments (mean postoperative pain score) · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review
Taste preference (patient preference) · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or other craniofacial…
1 finding from 1 review
Improvement in nutritional intake · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Restoration survival · Children, adolescents and adults with caries in deciduous and permanent teeth (age 3.5 to 84 years)
It is very uncertain whether laser (Er:YAG, Er,Cr:YSGG, or Nd:YAG) changes durability of restoration compared with conventional mechanical caries removal (standard drill; handpiece… (very low certainty).
3 findings from 1 review
Somnolence · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether anticonvulsants (gabapentin + alpha lipoic acid) changes adverse effects: drowsiness compared with placebo (very low certainty).
1 finding from 1 review
Height loss of interdental papilla - 1 year · People requiring retreatment of periapical lesions (failed root canal therapy)
It is very uncertain whether papilla base incision (PBI) changes height loss of interdental papilla - 1 year compared with complete papilla mobilisation (sulcular incision) (very low certainty).
1 finding from 1 review
Side effects / tolerability · Children with obstructive sleep apnoea (aged 15 years or younger)
1 finding from 1 review
Tolerability: 73.7% fitted with oral appliance (14/19 children) tolerated the treatment well and 26.3% (five children) discontinued therapy. Side effects: the included study did not assess this outcome.
1 study · 19 participants
GRADE not reported
Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adults undergoing orthodontic treatment
Brain wave music (BWM) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no special instructions (control); GRADE not reported.
3 findings from 1 review
MD -4.72 [-15.83, 6.39]
1 study · 24 participants
GRADE not reported
MD -26.65 [-39.06, -14.24]
1 study · 24 participants
Very low
MD -23.44 [-36.82, -10.06]
1 study · 24 participants
GRADE not reported
Change in QoL - anxiety (surrogate marker) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
It is very uncertain whether physical barriers (tongue protector) changes change in QoL - anxiety (surrogate marker) compared with placebo (very low certainty).
1 finding from 1 review
Oral health-related behaviour of residents · Nursing home residents (mean age 78.3 to 86.0 years; more than 66% women; 62.1% to 87.3% with dental prostheses)
1 finding from 1 review
One study (Bellomo 2005) assessed oral health-related behaviour of residents; 60 residents were interviewed about toothbrushing habits. Use of toothbrushes and the frequency of brushing during the study period were…
1 study · 60 participants
GRADE not reported
Need for analgesic prescription for pain (supplemental analgesic requirements) · Children up to 13 years of age, undergoing cleft lip repair surgery
It is very uncertain whether perioperative infraorbital nerve block changes need for analgesic prescription for pain (supplemental analgesic… compared with intravenous analgesia (very low certainty).
1 finding from 1 review
Healing of osteonecrosis - improvement ('healed' or 'improved' vs 'unchanged' or 'worse') · People of any age and either sex, in any setting, with BRONJ; bisphosphonate exposure past or current; includes people with cancer and…
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
0 studies
No studies found
Heart rate, respiratory rate, and blood pressure · Children up to 13 years of age, undergoing cleft lip repair surgery
1 finding from 1 review
Ahuja 1994: no significant difference in heart rate, respiratory rate, and blood pressure between groups. Takmaz 2009: no differences in respiratory rate and blood pressure, but children in the placebo group had…
2 studies
GRADE not reported