Findings

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Evidence found and GRADE certainty

4,411 questions · 5,986 findings · 226 reviews · Oral Health

No studies found 1,305 · 21.8%GRADE not reported 2,988 · 49.9%Very low 1,030 · 17.2%Low 476 · 8%Moderate 156 · 2.6%High 31 · 0.5%

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Dietary supplements (Catuama herbal compound) vs placebo

Somnolence · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether dietary supplements (Catuama herbal compound) changes adverse effects: drowsiness compared with placebo (very low certainty).

1 finding from 1 review

Motivational interview plus oral health education vs Oral health education

Self regulation: Average score (Treatment Self Regulation Questionnaire, high score = good) · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…

Motivational interview plus oral health education showed no clear difference in self regulation: Average score (Treatment Self Regulation… compared with oral health education; GRADE not reported.

3 findings from 1 review

Monitoring (any means of observation, supervision, keeping under review, measuring or testing at intervals) vs No monitoring

Service use: Emergency medical/dental treatment · People with serious mental illness (all included participants had schizophrenia); majority aged 18 to 65 years per NIMH 1987, or with…

The review found no eligible studies for this question.

1 finding from 1 review

Post‐treatment communication (text messaging) vs No communication (no text message)

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
1 finding from 1 review

Vibratory stimulation (vibratory adjuncts) vs No vibration or placebo vibration

Patient‐reported pain intensity or pain relief (VAS, NRS or categorical scale) · Adolescents and adults undergoing orthodontic treatment

Vibratory stimulation (vibratory adjuncts) showed no clear difference in patient‐reported pain intensity or pain relief (VAS, NRS or… compared with no vibration or placebo vibration; GRADE not reported.

5 findings from 1 review
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Benzodiazepines (topical clonazepam) vs placebo

Somnolence · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether benzodiazepines (topical clonazepam) changes adverse effects: drowsiness compared with placebo (very low certainty).

1 finding from 1 review

Zinc polycarboxylate cement vs Any other orthodontic band adhesive

Outcome not reported · Patients with full arch fixed orthodontic appliances with bands attached to molars (patients with cleft lip/palate or other craniofacial…

The review found no eligible studies for this question.

1 finding from 1 review

Educational intervention with information only (theoretical dental health education, no practical training) vs usual care

Denture plaque · Residents of institutions for elderly people (nursing staff and residents took part in the education programme)
1 finding from 1 review

Herbal extracts (tea components; Chinese herbal mixture; freeze-dried black raspberry gel) vs placebo or no treatment

Clinical resolution (oral lesion not completely resolved) · People with a diagnosis of oral leukoplakia
1 finding from 1 review
  • SoF 4, Clinical resolution (not completely resolved) at 3 to 6 months: '3 studies (freeze-dried black raspberry gel, green tea extract capsules, mixed tea) did not find evidence of benefit.' No GRADE. Effects text:…
    4 studies
    GRADE not reported

Root-end resection (with or without root-end filling; surgical retreatment) vs Non-surgical re-treatment (orthograde root canal therapy)

Healing rate · People with one or more endodontically treated teeth and a periapical condition requiring retreatment

Root-end resection (with or without root-end filling; surgical… showed no clear difference in healing - 10 years compared with root canal retreatment (non-surgical/orthograde); GRADE not reported.

2 findings from 1 review

Educational intervention with information and practical components (theoretical oral health education plus practical skills training) for nursing staff and/or residents vs (Optimised) usual care

Oral health · Nursing home residents (mean age 78.3 to 86.0 years; more than 66% women; 62.1% to 87.3% with dental prostheses)

The review found no eligible studies for this question.

1 finding from 1 review

Benzodiazepines (topical clonazepam) vs placebo

Adverse effects: dry mouth · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether benzodiazepines (topical clonazepam) changes adverse effects: dry mouth compared with placebo (very low certainty).

1 finding from 1 review

Preoperative analgesics (analgesics given before dental treatment) vs Placebo or no analgesics

Intraoperative pain · Children and adolescents aged up to 17 years having dental treatment (orthodontic treatment, fillings, pulp treatment, or tooth…

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative infraorbital nerve block vs Intravenous analgesia

Time to feeding after surgery · Children up to 13 years of age, undergoing cleft lip repair surgery

Perioperative infraorbital nerve block may leads to lower time to feeding after surgery (in minutes) compared with intravenous analgesia (low certainty).

1 finding from 1 review

Oral appliance or functional orthopaedic appliance vs placebo or no treatment

Nocturnal symptom: nightmares (questionnaire) · Children with obstructive sleep apnoea (aged 15 years or younger)

Oral appliance or functional orthopaedic appliance showed no clear difference in nocturnal symptom: nightmares (questionnaire) compared with placebo or no treatment; GRADE not reported.

1 finding from 1 review

Educational intervention with information and practical components (theoretical oral health education plus practical skills training) for nursing staff and/or residents vs (Optimised) usual care

Adverse effects of the interventions · Nursing home residents (mean age 78.3 to 86.0 years; more than 66% women; 62.1% to 87.3% with dental prostheses)

The review found no eligible studies for this question.

1 finding from 1 review

Preoperative ibuprofen vs placebo

Postoperative pain (continuous measure: self report using visual analogue scale) · Children and adolescents having orthodontic separator placement (without local anaesthetic)

Preoperative ibuprofen may leads to lower postoperative pain (continuous measure: self report using visual… compared with placebo (low certainty).

1 finding from 1 review

Systemic beta carotene or carotenoids (incl. lycopene) vs placebo or no treatment

Improvement of histological features (not improved) · People with a diagnosis of oral leukoplakia

Systemic beta carotene or carotenoids (incl. lycopene) may leads to lower improvement of histological features (not improved) compared with placebo or no treatment (low certainty).

1 finding from 1 review