Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,584 questions · 3,695 findings · 567 reviews

No studies found 784 · 21.2%GRADE not reported 308 · 8.3%Very low 1,036 · 28%Low 971 · 26.3%Moderate 440 · 11.9%High 156 · 4.2%

Intervention not reported

Case‐control ‐ ADEM · children 9 months to 15 years old

The intervention showed no clear difference in case‐control ‐ ADEM (low certainty).

1 finding from 1 review

Intervention not reported

Self‐controlled case series (hospitalisations) ‐ hospitalisations ‐ risk period: 0 to 60 days · children 9 months to 15 years old

The intervention showed no clear difference in self‐controlled case series (hospitalisations) ‐ hospitalisations ‐… (low certainty).

1 finding from 1 review

Intervention not reported

Self‐controlled case series (GP visits) ‐ GP visit ‐ risk period: 0 to 5 days · children 9 months to 15 years old

The intervention may leads to higher self‐controlled case series (GP visits) ‐ GP visit ‐ risk period: 0… (low certainty).

1 finding from 1 review

Intervention not reported

Self‐controlled case series (GP visits) ‐ GP visit ‐ risk period: 6 to 60 days · children 9 months to 15 years old

The intervention showed no clear difference in self‐controlled case series (GP visits) ‐ GP visit ‐ risk period: 6… (low certainty).

1 finding from 1 review

Intervention not reported

Self‐controlled case series ‐ lobar pneumonia ‐ lobar pneumonia risk period (0 to 90 days) · children 9 months to 15 years old

The intervention may leads to lower self‐controlled case series ‐ lobar pneumonia ‐ lobar pneumonia risk… (low certainty).

1 finding from 1 review

Intervention not reported

Self‐controlled case series ‐ invasive bacterial infections ‐ invasive bacterial infections risk period (0 to 90 days) · children 9 months to 15 years old

The intervention showed no clear difference in self‐controlled case series ‐ invasive bacterial infections ‐… (low certainty).

1 finding from 1 review

Autologous blood or PRP vs placebo at 3 months' follow‐up

Treatment success (> 25% improvement in pain or function) · lateral elbow pain

It is very uncertain whether autologous blood or PRP changes treatment success (> 25% improvement in pain or function) compared with placebo at 3 months' follow‐up (very low certainty).

1 finding from 1 review

Autologous blood or PRP vs placebo at 3 months' follow‐up

Adverse events (pain and swelling at injection site and limitation of elbow movement following injection) · lateral elbow pain

Autologous blood or PRP showed no clear difference in adverse events (pain and swelling at injection site and limitation… compared with placebo at 3 months' follow‐up (low certainty).

1 finding from 1 review