Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,454 questions · 3,562 findings · 816 reviews · Headline outcomes only

No studies found 538 · 15.1%GRADE not reported 239 · 6.7%Very low 933 · 26.2%Low 1,041 · 29.2%Moderate 612 · 17.2%High 199 · 5.6%

Intervention not reported

TXA given intravenously and intra‐articularly at a total dose of greater than 3 g pre‐incision, intraoperatively and postoperatively · individuals undergoing planned hip or knee replacement surgery Interventions: antifibrinolytics (tranexamic acid, aprotinin or…
1 finding from 1 review

Intervention not reported

Presence of PHN 6 months after the onset of acute herpetic rashClinical manifestation · people with acute herpes zoster (within 7 days of onset of rash)

It is very uncertain whether the intervention changes presence of PHN 6 months after the onset of acute herpetic… (very low certainty).

1 finding from 1 review

Intervention not reported

Serious adverse eventsClinical manifestation and laboratory examination · people with acute herpes zoster (within 7 days of onset of rash)

It is very uncertain whether the intervention changes serious adverse eventsClinical manifestation and laboratory… (very low certainty).

1 finding from 1 review

Intervention not reported

Non‐serious adverse eventsClinical manifestation and laboratory examination · people with acute herpes zoster (within 7 days of onset of rash)

The intervention showed no clear difference in non‐serious adverse eventsClinical manifestation and laboratory… (low certainty).

1 finding from 1 review

Videolaryngoscopy vs direct laryngoscopy

Non‐airway‐related adverse effects: desaturation or bradycardia episodes, or both · neonates (0 to 28 days of age) who needed tracheal intubation

It is very uncertain whether videolaryngoscopy changes non‐airway‐related adverse effects: desaturation or bradycardia… compared with conventional direct laryngoscopy (very low certainty).

1 finding from 1 review

Videolaryngoscopy vs direct laryngoscopy

Airway‐related adverse effects: airway trauma · neonates (0 to 28 days of age) who needed tracheal intubation

Videolaryngoscopy probably leads to lower airway‐related adverse effects: airway trauma compared with conventional direct laryngoscopy (moderate certainty).

1 finding from 1 review

Cilostazol vs aspirin

MACE · adults within 180 days of non‐cardioembolic ischaemic stroke or transient ischaemic attack and a clinical history of prior intracerebral…

Summary of findings table ‐ Cilostazol showed no clear difference in MACE compared with aspirin (low certainty).

1 finding from 1 review

Cilostazol vs aspirin

Death · adults within 180 days of non‐cardioembolic ischaemic stroke or transient ischaemic attack and a clinical history of prior intracerebral…

Summary of findings table ‐ Cilostazol showed no clear difference in death compared with aspirin (low certainty).

1 finding from 1 review

Cilostazol vs aspirin

Intracerebral haemorrhage (ICH) · adults within 180 days of non‐cardioembolic ischaemic stroke or transient ischaemic attack and a clinical history of prior intracerebral…

Summary of findings table ‐ Cilostazol showed no clear difference in intracerebral haemorrhage (ICH) compared with aspirin (low certainty).

1 finding from 1 review