Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,696 questions · 3,815 findings · 855 reviews

No studies found 573 · 15%GRADE not reported 374 · 9.8%Very low 993 · 26%Low 1,062 · 27.8%Moderate 614 · 16.1%High 199 · 5.2%

Human deoxyribonuclease vs placebo

Clinical failure Number of children with no significant improvement in cough diary scores at two weeks (average of day 13 to 14) · children with primary (intrinsic) tracheomalacia

Human deoxyribonuclease showed no clear difference in clinical failure Number of children with no significant improvement… compared with placebo (low certainty).

1 finding from 1 review

Intervention not reported

Inpatient and 30 day mortality ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery

It is very uncertain whether the intervention changes inpatient and 30 day mortality ‐ Colon cancer (very low certainty).

1 finding from 1 review

Intervention not reported

Inpatient and 30 day mortality ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery

The intervention showed no clear difference in inpatient and 30 day mortality ‐ Rectal cancer (low certainty).

1 finding from 1 review

Intervention not reported

Inpatient and 30 day mortality ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery

The intervention may leads to lower inpatient and 30 day mortality ‐ Colorectal cancer (low certainty).

1 finding from 1 review

Intervention not reported

Inpatient and 30 day mortality ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery

It is very uncertain whether the intervention changes inpatient and 30 day mortality ‐ Colorectal cancer (very low certainty).

1 finding from 1 review

Intervention not reported

Inpatient and 30 day mortality ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery

It is very uncertain whether the intervention changes inpatient and 30 day mortality ‐ Colon cancer (very low certainty).

1 finding from 1 review

Intervention not reported

Inpatient and 30 day mortality ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery

It is very uncertain whether the intervention changes inpatient and 30 day mortality ‐ Rectal cancer (very low certainty).

1 finding from 1 review

Intervention not reported

Neurological sequelae at day 28 · Children with severe malaria

The intervention showed no clear difference in neurological sequelae at day 28 (moderate certainty).

1 finding from 1 review

Intervention not reported

Neurological sequelae at day 28 · Adults with severe malaria

The review found no eligible studies for this question.

1 finding from 1 review