Gap finder

Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

2,206 questions in 117 reviews · Common Mental Disorders

current versions
No studies 387 · 17.5%Ungraded 111 · 5%Very low 635 · 28.8%Low 568 · 25.7%Moderate 449 · 20.4%High 56 · 2.5%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
CBT vs treatment
Reduction in depressive symptoms post‐treatment · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extractedNRNo studies
CBT vs treatment
Improvement in global functioning post‐treatment · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extractedNRNo studies
CBT vs treatment
Adverse events (randomisation to post‐treatment) · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extractedNRNo studies
CBT vs attention control
Remission of primary anxiety diagnosis post‐treatment (ITT) · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
OR 2.28 [1.33, 3.89]10 studies · 822 participantsLow
CBT vs attention control
Acceptability (number of participants lost to post‐treatment assessment) · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
OR 1 [0.68, 1.49]12 studies · 797 participantsLow
CBT vs attention control
Remission of all anxiety diagnoses post‐treatment (ITT) · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
OR 2.75 [1.22, 6.17]5 studies · 378 participantsLow
CBT vs waitlist
Acceptability (number of participants lost to post‐treatment assessment) · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
OR 1.09 [0.85, 1.41]45 studies · 3158 participantsLow
CBT vs attention control
Reduction in anxiety symptoms (child report) post‐treatment · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extracted15 studies · 978 participantsModerate
CBT vs attention control
Reduction in anxiety symptoms (parent report) post‐treatment · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extracted8 studies · 638 participantsLow
CBT vs attention control
Reduction in depressive symptoms post‐treatment · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extracted10 studies · 613 participantsLow
CBT vs attention control
Improvement in global functioning post‐treatment · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extractedNRNo studies
CBT vs attention control
Adverse events (randomisation to post‐treatment) · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extractedNRNo studies
CBT vs alternative treatment
Remission of primary anxiety diagnosis post‐treatment (ITT) · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extractedNRNo studies
CBT vs alternative treatment
Acceptability (number of participants lost to post‐treatment assessment) · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
OR 1.58 [0.61, 4.13]7 studies · 515 participantsLow
CBT vs alternative treatment
Remission of all anxiety diagnoses post‐treatment (ITT) · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
OR 0.89 [0.35, 2.23]4 studies · 401 participantsLow
CBT vs alternative treatment
Reduction in anxiety symptoms (child report) post‐treatment · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extracted6 studies · 399 participantsLow
CBT vs alternative treatment
Reduction in anxiety symptoms (parent report) post‐treatment · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extracted6 studies · 423 participantsLow
CBT vs waitlist
Remission of all anxiety diagnoses post‐treatment (ITT) · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
OR 4.43 [2.89, 6.78]28 studies · 2075 participantsModerate
CBT vs alternative treatment
Reduction in depressive symptoms post‐treatment · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extractedNRNo studies
CBT vs alternative treatment
Improvement in global functioning post‐treatment · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extractedNRNo studies
CBT vs alternative treatment
Adverse events (randomisation to post‐treatment) · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extractedNRNo studies
CBT vs waitlist
Reduction in anxiety symptoms (child report) post‐treatment · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extracted45 studies · 2831 participantsLow
CBT vs waitlist
Reduction in anxiety symptoms (parent report) post‐treatment · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extracted35 studies · 2137 participantsLow
CBT vs waitlist
Reduction in depressive symptoms post‐treatment · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extracted17 studies · 1157 participantsModerate
CBT vs waitlist
Improvement in global functioning post‐treatment · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extracted11 studies · 557 participantsLow
CBT vs waitlist
Adverse events (randomisation to post‐treatment) · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
no estimate extractedNRNo studies
CBT vs treatment
Remission of primary anxiety diagnosis post‐treatment (ITT) · children and adolescents with anxiety disorders
Cognitive behavioural therapy for anxiety disorders in children and adolescents (2020) · Cochrane
OR 3.19 [0.9, 11.29]8 studies · 487 participantsLow
Behavioural activation vs CBT
treatment efficacyup to 6 months (5‐16 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
RR 0.99 [0.92, 1.07]5 studies · 601 participantsModerate
Behavioural activation vs third‐wave CBT
depression symptoms (continuous) up to 6 months (4‐8 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
no estimate extracted3 studies · 147 participantsLow
Behavioural activation vs third‐wave CBT
quality of life (continuous)up to 6 months (8 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
no estimate extracted1 study · 81 participantsLow
Behavioural activation vs third‐wave CBT
anxiety symptoms (continuous)up to 6 months (4‐8 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
no estimate extracted3 studies · 147 participantsLow
Behavioural activation vs humanistic therapy
treatment efficacyup to 6 months (8‐10 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
RR 1.84 [1.15, 2.95]2 studies · 46 participantsLow
Behavioural activation vs humanistic therapy
treatment acceptabilityup to 6 months (2‐10 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
RR 1.06 [0.2, 5.55]2 studies · 96 participantsVery low
Behavioural activation vs humanistic therapy
depression symptoms(continuous) up to 6 months (2‐10 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
no estimate extracted3 studies · 93 participantsModerate
Behavioural activation vs humanistic therapy
quality of life (continuous)up to 6 months (2 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
no estimate extracted1 study · 50 participantsLow
Behavioural activation vs humanistic therapy
anxiety symptoms (continuous)up to 6 months (2 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
no estimate extracted1 study · 50 participantsLow
Behavioural activation vs psychodynamic
treatment efficacy up to 6 months (12 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
RR 1.21 [0.74, 1.99]1 study · 60 participantsVery low
Behavioural activation vs psychodynamic
depression symptoms(continuous) up to 6 months (12 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
no estimate extracted1 study · 60 participantsVery low
Behavioural activation vs CBT
treatment acceptability up to 6 months (4‐16 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
RR 1.03 [0.85, 1.25]12 studies · 1195 participantsLow
Behavioural activation vs psychodynamic
social adjustment and functioning(continuous) up to 6 months (12 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
no estimate extracted1 study · 60 participantsVery low
Behavioural activation vs interpersonal, cognitive analytic, integrative
treatment acceptabilityup to 6 months (4‐12 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
RR 0.84 [0.32, 2.2]4 studies · 123 participantsVery low
Behavioural activation vs interpersonal, cognitive analytic, integrative
depression symptoms (continuous) up to 6 months (4‐12 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
no estimate extracted4 studies · 103 participantsVery low
Behavioural activation vs interpersonal, cognitive analytic, integrative
social adjustment and functioning (continuous)up to 6 months (12 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
no estimate extracted1 study · 39 participantsVery low
Behavioural activation vs interpersonal, cognitive analytic, integrative
anxiety symptoms (continuous) up to 6 months (4 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
no estimate extracted1 study · 15 participantsVery low
Behavioural activation vs interpersonal, cognitive analytic, integrative
adverse events(12 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
no estimate extracted1 study · 24 participantsLow
Behavioural activation vs waiting list
treatment efficacyup to 6 months (4 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
RR 2.14 [0.9, 5.09]1 study · 26 participantsLow
Behavioural activation vs waiting list
treatment acceptabilityup to 6 months (1 to 10 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
RR 1.17 [0.7, 1.93]8 studies · 359 participantsModerate
Behavioural activation vs waiting list
depression symptoms(continuous) up to 6 months (1 to 10 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
no estimate extracted12 studies · 619 participantsLow
Behavioural activation vs waiting list
quality of life (continuous)up to 6 months (8 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
no estimate extracted1 study · 80 participantsLow
Behavioural activation vs CBT
depression symptoms (continuous) up to 6 months (4‐16 weeks) · depression in adults
Behavioural activation therapy for depression in adults (2020) · Cochrane
no estimate extracted16 studies · 1205 participantsModerate