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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
759 questions in 57 reviews · Colorectal
current versionsNo studies 91 · 12%Ungraded 12 · 1.6%Very low 209 · 27.5%Low 229 · 30.2%Moderate 160 · 21.1%High 58 · 7.6%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Intervention NR Abdominoperineal excision of the rectum rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | OR 0.55 [0.42, 0.72] | 1 study · 894 participants | Very low |
Intervention NR Overall five year survival ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | HR 0.87 [0.82, 0.92] | 2 studies · 15462 participants | Low |
Intervention NR Overall five year survival ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | HR 0.84 [0.76, 0.93] | 1 study · 2905 participants | Low |
Intervention NR Overall five year survival ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | HR 0.99 [0.86, 1.14] | 1 study · 1903 participants | Low |
Intervention NR Five year disease specific survival ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | HR 0.94 [0.78, 1.13] | 1 study · 1416 participants | Low |
Intervention NR Inpatient and 30 day mortality ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | OR 0.79 [0.61, 1.02] | 3 studies · 47584 participants | Very low |
Intervention NR Inpatient and 30 day mortality ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | OR 0.79 [0.51, 1.22] | 1 study · 1903 participants | Low |
Intervention NR Anastomotic leak rate ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | OR 0.66 [0.36, 1.21] | 1 study · 2570 participants | Low |
Intervention NR Anastomotic leak rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | OR 0.61 [0.29, 1.28] | 1 study · 1929 participants | Low |
Intervention NR Overall five year survival ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | HR 0.97 [0.77, 1.22] | 2 studies · 5211 participants | Very low |
Intervention NR Permanent stoma rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | OR 0.65 [0.46, 0.91] | 1 study · 1323 participants | Low |
Intervention NR Abdominoperineal excision of rectum rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | OR 0.2 [0.1, 0.4] | 1 study · 180 participants | Very low |
Intervention NR Overall five year survival ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | HR 0.81 [0.71, 0.94] | 4 studies · 14628 participants | Low |
Intervention NR Five year disease specific survival ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | HR 0.74 [0.62, 0.88] | 1 study · 2186 participants | Low |
Intervention NR Inpatient and 30 day mortality ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | OR 0.74 [0.6, 0.91] | 2 studies · 11973 participants | Low |
Intervention NR Five year local recurrence rate ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | HR 0.56 [0.44, 0.71] | 1 study · 2587 participants | Low |
Intervention NR Anastomotic leak rate ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | OR 0.71 [0.31, 1.63] | 2 studies · 8563 participants | Very low |
Intervention NR Permanent stoma rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | OR 0.7 [0.53, 0.94] | 1 study · 2026 participants | Low |
Intervention NR Overall five year survival ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | HR 0.85 [0.77, 0.95] | 3 studies · 4028 participants | Low |
Intervention NR Inpatient and 30 day mortality ‐ Colorectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | OR 0.98 [0.79, 1.2] | 3 studies · 77823 participants | Very low |
Intervention NR Inpatient and 30 day mortality ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | OR 0.89 [0.78, 1.01] | 7 studies · 263071 participants | Very low |
Intervention NR Inpatient and 30 day mortality ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | OR 1.07 [0.76, 1.5] | 5 studies · 14941 participants | Very low |
Intervention NR Five year local recurrence rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | HR 0.77 [0.51, 1.16] | 3 studies · 2986 participants | Very low |
Intervention NR Anastomotic leak rate ‐ Colon cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | OR 1.44 [0.8, 2.59] | 1 study · 2808 participants | Low |
Intervention NR Anastomotic leak rate ‐ Rectal cancer · Patients with outcomes after colorectal cancer surgery Workload and surgeon´s specialty for outcome after colorectal cancer surgery (2012) · Cochrane | OR 0.72 [0.48, 1.09] | 2 studies · 2615 participants | Low |
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis Anastomotic leak Odds ratio · patients with Bowel resection Single layer versus double layer suture anastomosis of the gastrointestinal tract (2012) · Cochrane | OR 0.76 [0.44, 1.32] | 7 studies · 842 participants | Very low |
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis Anastomosis time Mean difference · patients with Bowel resection Single layer versus double layer suture anastomosis of the gastrointestinal tract (2012) · Cochrane | no estimate extracted | 2 studies · 218 participants | Low |
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis Length of hospital stay Mean difference · patients with Bowel resection Single layer versus double layer suture anastomosis of the gastrointestinal tract (2012) · Cochrane | no estimate extracted | 3 studies · 390 participants | Low |
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis Mortality Odds ratio · patients with Bowel resection Single layer versus double layer suture anastomosis of the gastrointestinal tract (2012) · Cochrane | OR 0.56 [0.19, 1.63] | 4 studies · 403 participants | Low |
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis Major complications Odds ratio · patients with Bowel resection Single layer versus double layer suture anastomosis of the gastrointestinal tract (2012) · Cochrane | OR 0.71 [0.44, 1.16] | 7 studies · 842 participants | Low |
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis Anastomotic leak in high quality trials Odds ratio · patients with Bowel resection Single layer versus double layer suture anastomosis of the gastrointestinal tract (2012) · Cochrane | OR 1.13 [0.42, 3.01] | 3 studies · 353 participants | Moderate |
Single layer gastrointestinal anastomosis vs Double layer gastrointestinal anastomosis Anastomotic leak in poor quality trials Odds ratio · patients with Bowel resection Single layer versus double layer suture anastomosis of the gastrointestinal tract (2012) · Cochrane | OR 0.63 [0.32, 1.24] | 4 studies · 489 participants | Very low |
Intervention NR Total Successful Intubation Rate · patients with Transparent Cap Colonoscopy versus Standard Colonoscopy to Improve Caecal Intubation (2012) · Cochrane | OR 1.36 [0.95, 1.93] | 12 studies · 5932 participants | Moderate |
Sensitivity Analysis; Stretch vs Sphincterotomy excluding Marby & Weaver Persistance of the Fissure · patients with fissure in ano Operative procedures for fissure in ano (2011) · Cochrane | OR 4.42 [1.75, 11.18] | 5 studies · 328 participants | Moderate |
Sensitivity Analysis; Stretch vs Sphincterotomy excluding Marby & Weaver Minor incontinence to flatus · patients with fissure in ano Operative procedures for fissure in ano (2011) · Cochrane | OR 5.73 [2.31, 14.2] | 5 studies · 309 participants | Low |
Open vs closed partial lateral internal sphincterotomy Persistence of the anal fissure · patients with fissure in ano Operative procedures for fissure in ano (2011) · Cochrane | OR 1 [0.4, 2.48] | 5 studies · 336 participants | High |
Open vs closed partial lateral internal sphincterotomy Minor incontinence to flatus · patients with fissure in ano Operative procedures for fissure in ano (2011) · Cochrane | OR 0.87 [0.41, 1.83] | 5 studies · 336 participants | Moderate |
Primary analyses ERAS vs conventional Mortality outpatient · patients with colorectal surgery Fast track surgery versus conventional recovery strategies for colorectal surgery (2011) · Cochrane | RR 0.53 [0.12, 2.38] | 4 studies · 237 participants | High |
Primary analyses ERAS vs conventional Complications clinical scoring · patients with colorectal surgery Fast track surgery versus conventional recovery strategies for colorectal surgery (2011) · Cochrane | RR 0.5 [0.35, 0.72] | 4 studies · 577 participants | Very low |
Primary analyses ERAS vs conventional Readmissions · patients with colorectal surgery Fast track surgery versus conventional recovery strategies for colorectal surgery (2011) · Cochrane | RR 0.87 [0.08, 9.39] | 4 studies · 237 participants | Low |
Primary analyses ERAS vs conventional hospital stay days of hospital admittance. Scale from: 1 to 100. · patients with colorectal surgery Fast track surgery versus conventional recovery strategies for colorectal surgery (2011) · Cochrane | no estimate extracted | 4 studies · 237 participants | Very low |
IAS preserving seton vs Conventional seton Recurrence · patients with anorectal fistula Surgical intervention for anorectal fistula (2010) · Cochrane | OR 1.88 [0.15, 22.88] | 1 study · 34 participants | Moderate |
Fistulotomy vs Marsupialization fistulotomy Incontinence · patients with anorectal fistula Surgical intervention for anorectal fistula (2010) · Cochrane | OR 2.29 [0.66, 7.97] | 2 studies · 137 participants | Moderate |
Advancement flap vs Fibrin glue with Flap repair Recurrence · patients with anorectal fistula Surgical intervention for anorectal fistula (2010) · Cochrane | OR 0.29 [0.09, 0.92] | 1 study · 58 participants | High |
Advancement flap vs Fibrin glue with Flap repair Incontinence · patients with anorectal fistula Surgical intervention for anorectal fistula (2010) · Cochrane | no estimate extracted | 1 study · 58 participants | High |
Fistulotomy vs Fistulectomy Recurrence · patients with anorectal fistula Surgical intervention for anorectal fistula (2010) · Cochrane | OR 1.36 [0.2, 9.02] | 1 study · 45 participants | Moderate |
Fistulotomy vs Fistulectomy Incontinence · patients with anorectal fistula Surgical intervention for anorectal fistula (2010) · Cochrane | OR 0.26 [0.02, 2.72] | 1 study · 45 participants | Moderate |
Island flap anoplasty vs Fistulotomy / seton Recurrence · patients with anorectal fistula Surgical intervention for anorectal fistula (2010) · Cochrane | no estimate extracted | 1 study · 20 participants | High |
Island flap anoplasty vs Fistulotomy / seton Incontinence · patients with anorectal fistula Surgical intervention for anorectal fistula (2010) · Cochrane | no estimate extracted | 1 study · 20 participants | High |
IAS preserving seton vs Conventional seton Incontinence · patients with anorectal fistula Surgical intervention for anorectal fistula (2010) · Cochrane | OR 0.41 [0.03, 5.03] | 1 study · 34 participants | Moderate |