Clinical success (survival free of symptoms) at 24 months · Adults with asymptomatic teeth with vital carious pulp exposures
1 finding from 1 review
Shovelton 1971 (Analysis 1.1): 275 teeth followed for 2 years (235 at 6 months, 160 at 12 months, 85 analysed at 24 months). Success rates 50% to 80%. Ledermix and calcium hydroxide had the highest success rates,…
1 study · 275 participants
GRADE not reported
Clinical success (survival free of symptoms) at 24 months · Adults with asymptomatic teeth with vital carious pulp exposures
1 finding from 1 review
Shovelton 1971 (Analysis 1.1): 275 teeth followed for 2 years (235 at 6 months, 160 at 12 months, 85 analysed at 24 months). Success rates 50% to 80%. Ledermix and calcium hydroxide had the highest success rates,…
1 study · 275 participants
GRADE not reported
Participants' global self‐assessment of acne improvement · participants with acne
It is very uncertain whether azelaic acid changes participants' global self‐assessment of acne improvement Improved to… compared with adapalene (very low certainty).
1 finding from 1 review
Treatment withdrawal · participants with acne
Azelaic acid showed no clear difference in withdrawal for any reason (long term: treatment duration > 8 weeks) compared with clindamycin (low certainty).
1 finding from 1 review
Minor adverse events · participants with acne
Azelaic acid showed no clear difference in total number of participants who experienced at least one minor… compared with clindamycin (low certainty).
1 finding from 1 review
Quality of life · participants with acne
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participants' global self‐assessment of acne improvement Good to excellent improvement (long term: treatment duration > 8 weeks) · participants with acne
Azelaic acid showed no clear difference in participants' global self‐assessment of acne improvement Good to… compared with tretinoin (moderate certainty).
1 finding from 1 review
Treatment withdrawal · participants with acne
Azelaic acid showed no clear difference in withdrawal for any reason (long term: treatment duration > 8 weeks) compared with tretinoin (low certainty).
1 finding from 1 review
Minor adverse events · participants with acne
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life · participants with acne
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participants' global self‐assessment of acne improvement · participants with acne
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Withdrawal for any reason (medium term: treatment duration from 5 to 8 weeks) · participants with acne
1 finding from 1 review
Minor adverse events · participants with acne
It is very uncertain whether salicylic acid changes total number of participants who experienced at least one minor… compared with benzoyl peroxide (very low certainty).
1 finding from 1 review
Treatment withdrawal · participants with acne
It is very uncertain whether azelaic acid changes withdrawal for any reason (long term: treatment duration > 8 weeks) compared with adapalene (very low certainty).
1 finding from 1 review
Quality of life (change from baseline) in the medium term · participants with acne
1 finding from 1 review
Participants' global self‐assessment of acne improvement Good to excellent improvement (medium term: treatment duration from 5 to 8 weeks) · participants with acne
It is very uncertain whether salicylic acid changes participants' global self‐assessment of acne improvement Good to… compared with pyruvic acid (very low certainty).
1 finding from 1 review
Withdrawal for any reason (medium term: treatment duration from 5 to 8 weeks) · participants with acne
Salicylic acid showed no clear difference in withdrawal for any reason (medium term: treatment duration from 5 to… compared with pyruvic acid (low certainty).
1 finding from 1 review
Minor adverse events · participants with acne
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Quality of life · participants with acne
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Participants' global self‐assessment of acne improvement Moderate to excellent improvement (long term: treatment duration > 8 weeks) · participants with acne
Salicylic acid showed no clear difference in participants' global self‐assessment of acne improvement Moderate to… compared with tretinoin (low certainty).
1 finding from 1 review