Caries increment, surface index D(M)FS · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
2400 to 2800 ppm F toothpaste showed no clear difference in caries increment, surface index D(M)FS compared with 1450 to 1500 ppm F toothpaste (moderate certainty).
1 finding from 1 review
SMD -0.05 [-0.14, 0.05]
2 studies
Moderate
Caries increment, surface index D(M)FS · Children and adolescents with immature permanent dentition (aged 5 to 16 years at study start)
440 to 550 ppm F toothpaste showed no clear difference in caries increment, surface index D(M)FS compared with 250 ppm F toothpaste (low certainty).
1 finding from 1 review
SMD 0.03 [-0.17, 0.23]
1 study
Low
Decayed, missing, filled surfaces (DMFS) · pregnant women
Women who experienced preterm birth did not have a significantly different DMFS than those who did not (mean difference -0.15, 95% CI -3.40 to 3.09; 3 studies; I2=89%); certainty of evidence not graded.
1 finding from 1 review
Reduction in pressure ulcer surface area · people with pressure ulcers residing in long‐term‐care facilities
1 finding from 1 review
Total lesion area divided by total surface area (visual) · Patients with early caries lesions in permanent teeth (non-fluoridated water area)
Adding CPP-ACP to fluorides did not significantly change the lesion-area outcome for smooth-surface early caries lesions versus fluorides alone; not GRADE-rated.
1 finding from 1 review
Filled primary surfaces at 3 years · Pregnant women (for preventing dental caries in the primary teeth of their children)
Fluoride supplementation (tablets, drops, lozenges or chewing gum) showed no clear difference in filled primary surfaces at 5 years compared with placebo or no treatment; GRADE not reported.
2 findings from 1 review
Caries on occlusal surfaces of permanent molars (12 months) · Children and adolescents (general population, aged under 20 years)
Resin-based fissure sealant (2nd/3rd/4th generation) led to lower caries on occlusal surfaces of permanent molars (36 months) compared with no sealant (control/no treatment); GRADE not reported.
3 findings from 1 review
OR 0.17 [0.11, 0.27]
7 studies
GRADE not reported
OR 0.21 [0.16, 0.28]
4 studies
GRADE not reported
OR 0.17 [0.10, 0.30]
7 studies
GRADE not reported
Missing primary surfaces (ms) · Pregnant women (for preventing dental caries in the primary teeth of their children)
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Decayed primary surfaces at 3 years · Pregnant women (for preventing dental caries in the primary teeth of their children)
Fluoride supplementation (tablets, drops, lozenges or chewing gum) showed no clear difference in decayed primary surfaces at 3 years compared with placebo or no treatment; GRADE not reported.
2 findings from 1 review
Ocular surface staining · adults with dry eye syndrome
1 finding from 1 review
Ocular surface staining · adults with dry eye syndrome
1 finding from 1 review
Ocular surface staining · adults with dry eye syndrome
1 finding from 1 review
Ocular surface staining · adults with dry eye syndrome
The review found no eligible studies for this question.
1 finding from 1 review
Ocular surface staining · mostly women with dry eye syndrome
1 finding from 1 review
Ocular surface staining · adults with dry eye syndrome
1 finding from 1 review
Ocular surface staining · adults with dry eye syndrome
1 finding from 1 review
Ocular surface staining · adults with dry eye syndrome
1 finding from 1 review
Intervention not reported
Elimination of all clinical signs of ocular surface inflammation ('complete success'), preferably measured by a composite grading system, at three months (± one month) after start of treatment · children with blepharokeratoconjunctivitis
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Improvement of clinical signs of ocular surface inflammation ('partial success'), preferably measured by a composite grading system, at three months (± one month) after start of treatment · children with blepharokeratoconjunctivitis
1 finding from 1 review
no estimate extracted
137 participants
Very low
Decayed or filled primary tooth surfaces at 3 years · Pregnant women (for preventing dental caries in the primary teeth of their children)
It is very uncertain whether fluoride supplementation (tablets, drops, lozenges or chewing gum) changes decayed or filled primary tooth surfaces at 3 years compared with placebo or no treatment (very low certainty).
1 finding from 1 review