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Evidence found and GRADE certainty

949 questions · 1,008 findings · 130 reviews · Gynaecology and Fertility

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No studies found 195 · 19.3%GRADE not reported 30 · 3%Very low 346 · 34.3%Low 323 · 32%Moderate 101 · 10%High 13 · 1.3%

Aqueous subcutaneous (Sc) progesterone vs vaginal progesterone

Ongoing pregnancy · women trying to conceive by intrauterine insemination

It is very uncertain whether aqueous subcutaneous (Sc) progesterone changes ongoing pregnancy rate compared with vaginal progesterone gel (very low certainty).

1 finding from 1 review

Progesterone vs no treatment or placebo (route of progesterone administration)

Clinical pregnancy · women trying to conceive by intrauterine insemination

Progesterone may leads to higher clinical pregnancy per woman compared with no treatment or placebo (route of progesterone administration) (low certainty).

1 finding from 1 review

Aqueous subcutaneous (Sc) progesterone vs vaginal progesterone

Clinical pregnancy rate · women trying to conceive by intrauterine insemination

It is very uncertain whether aqueous subcutaneous (Sc) progesterone changes clinical pregnancy rate compared with vaginal progesterone gel (very low certainty).

1 finding from 1 review

Subcutaneous (Sc) gonadotropin‐releasing hormone (GnRH) agonist vs placebo/no treatment

Ongoing pregnancy · women trying to conceive by intrauterine insemination

It is very uncertain whether subcutaneous (Sc) gonadotropin‐releasing hormone (GnRH) agonist changes ongoing pregnancy rate compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Subcutaneous (Sc) gonadotropin‐releasing hormone (GnRH) agonist vs placebo/no treatment

Clinical pregnancy rate · women trying to conceive by intrauterine insemination

It is very uncertain whether subcutaneous (Sc) gonadotropin‐releasing hormone (GnRH) agonist changes clinical pregnancy rate compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Subcutaneous (Sc) gonadotropin‐releasing hormone (GnRH) agonist vs placebo/no treatment

Multiple pregnancy rate · women trying to conceive by intrauterine insemination

It is very uncertain whether subcutaneous (Sc) gonadotropin‐releasing hormone (GnRH) agonist changes multiple pregnancy rate compared with placebo/no treatment (very low certainty).

1 finding from 1 review

Human chorionic gonadotropin (hCG) injection vs no treatment

Clinical pregnancy rate · women trying to conceive by intrauterine insemination

It is very uncertain whether human chorionic gonadotropin (hCG) injection changes clinical pregnancy rate compared with no treatment (very low certainty).

1 finding from 1 review

Human chorionic gonadotropin (hCG) injection vs no treatment

Multiple pregnancy rate · women trying to conceive by intrauterine insemination

It is very uncertain whether human chorionic gonadotropin (hCG) injection changes multiple pregnancy rate compared with no treatment (very low certainty).

1 finding from 1 review

Progesterone vs no treatment or placebo (route of progesterone administration)

Clinical pregnancy per woman ‐ oral route · women trying to conceive by intrauterine insemination

It is very uncertain whether progesterone changes clinical pregnancy per woman ‐ oral route compared with no treatment or placebo (route of progesterone administration) (very low certainty).

1 finding from 1 review

Progesterone vs no treatment or placebo (route of progesterone administration)

Multiple pregnancy rate · women trying to conceive by intrauterine insemination

Progesterone showed no clear difference in multiple pregnancy per woman compared with no treatment or placebo (route of progesterone administration) (low certainty).

1 finding from 1 review