Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

290 questions · 295 findings · 24 reviews · Haematology

No studies found 73 · 24.7%GRADE not reported 23 · 7.8%Very low 55 · 18.6%Low 96 · 32.5%Moderate 37 · 12.5%High 11 · 3.7%

Plerixafor vs placebo

Successful stem cell collection · People with haematopoietic stem cell mobilisation for autologous transplantation in malignant lymphoma or multiple myeloma

Plerixafor leads to higher successful stem cell collection compared with placebo (high certainty).

1 finding from 1 review

Plerixafor vs placebo

Adverse events (during stem cell mobilisation and collection) · People with haematopoietic stem cell mobilisation for autologous transplantation in malignant lymphoma or multiple myeloma

Plerixafor showed no clear difference in adverse events (during stem cell mobilisation and collection) compared with placebo (high certainty).

1 finding from 1 review

Eculizumab vs placebo

Adverse events (serious and nonserious) Medical Dictionary for Regulatory Activities (MedDRA) · patients with paroxysmal nocturnal hemoglobinuria

Eculizumab showed no clear difference in adverse events (serious and nonserious) Medical Dictionary for… compared with placebo (low certainty).

1 finding from 1 review