Intervention not reported
Time to first analgesic request (mean time in minutes) · adults undergoing surgery
1 finding from 1 review
Intervention not reported
Early acute postoperative pain (within 6 hours postoperatively using a validated pain scale: 0, no pain to 10, maximum pain) · adults undergoing surgery
1 finding from 1 review
Intervention not reported
Adverse events (Re‐operation for bleeding (reoperation for major bleeding within 30 days (yes/no))) · adults undergoing surgery
It is very uncertain whether the intervention changes adverse events (Re‐operation for bleeding (reoperation for major… (very low certainty).
1 finding from 1 review
Incidence of breast hematoma · women undergoing breast surgery
NSAID showed no clear difference in incidence of breast hematoma compared with placebo (low certainty).
1 finding from 1 review
Number of patients with postoperative nausea and vomiting (24 hours postoperatively) · women undergoing breast surgery
NSAID probably leads to lower incidence rate or severity of postoperative nausea, vomiting, or both compared with other analgesic (moderate certainty).
1 finding from 1 review
Bleeding from any location within 90 days · women undergoing breast surgery
It is very uncertain whether NSAID changes bleeding from any location within 90 days compared with other analgesic (very low certainty).
1 finding from 1 review
Other side effects of NSAID use · women undergoing breast surgery
It is very uncertain whether NSAID changes other side effects of NSAID use compared with other analgesic (very low certainty).
1 finding from 1 review
Opioid use within 24 (± 12) hours of surgery · women undergoing breast surgery
1 finding from 1 review
Pain intensity 24 (± 12) hours following surgery · women undergoing breast surgery
1 finding from 1 review
Pain intensity 24 (± 12) hours following surgery · women undergoing breast surgery
1 finding from 1 review
Number of patients with postoperative nausea and vomiting (24 hours postoperatively) · women undergoing breast surgery
NSAID showed no clear difference in incidence rate or severity of postoperative nausea, vomiting, or both compared with placebo (low certainty).
1 finding from 1 review
Bleeding from any location within 90 days · women undergoing breast surgery
NSAID showed no clear difference in bleeding from any location within 90 days compared with placebo (low certainty).
1 finding from 1 review
Blood transfusion · women undergoing breast surgery
It is very uncertain whether NSAID changes need for blood transfusion compared with placebo (very low certainty).
1 finding from 1 review
Other side effects of NSAID use · women undergoing breast surgery
NSAID showed no clear difference in other side effects of NSAID use compared with placebo (low certainty).
1 finding from 1 review
Opioid use within 24 (± 12) hours of surgery · women undergoing breast surgery
1 finding from 1 review
Incidence of breast hematoma · women undergoing breast surgery
It is very uncertain whether NSAID changes incidence of breast hematoma within 90 days of breast surgery compared with other analgesic (very low certainty).
1 finding from 1 review
Pain intensity 24 (± 12) hours following surgery · women undergoing breast surgery
1 finding from 1 review
Participant‐reported pain relief of 30% or greater · children and adolescents with chronic non‐cancer pain
1 finding from 1 review
Any adverse event · children and adolescents with chronic non‐cancer pain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Serious adverse event · children and adolescents with chronic non‐cancer pain
1 finding from 1 review