Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

466 questions · 492 findings · 33 reviews · Common Mental Disorders

No studies found 136 · 27.6%GRADE not reported 7 · 1.4%Very low 147 · 29.9%Low 133 · 27%Moderate 58 · 11.8%High 11 · 2.2%

New‐generation antidepressants vs placebo

Repetition of SH at post‐intervention · self‐harm in adults

It is very uncertain whether newer generation antidepressants (NGAs) changes repetition of SH by post‐intervention (NGA class)№ of participants:… compared with placebo (very low certainty).

3 findings from 1 review

Mood stabilisers vs placebo

Repetition of SH at post‐intervention · self‐harm in adults

It is very uncertain whether mood stabilisers, including antiepileptics and lithium changes repetition of SH by post‐intervention№ of participants: 167(1 RCT) compared with placebo (very low certainty).

1 finding from 1 review

Mindfulness vs no treatment or waiting list

Mental health and well‐being: stress or stress perceptionMeasured by: investigators measured stress or stress perception using different instruments; lower scores mean lower stress or stress perception Timing of outcome assessment: post‐intervention
1 finding from 1 review

Paradoxical intention therapy vs diazepam

Reduction in physical signs (number of patients without any conversive attacks in last 2 weeks) End of treatment · people with conversion disorder according to DSM‐IV or ICD‐10 criteria

It is very uncertain whether paradoxical intention therapy changes reduction in physical signs (number of patients without any… compared with diazepam (very low certainty).

1 finding from 1 review