Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

728 questions · 764 findings · 107 reviews

No studies found 194 · 25.4%GRADE not reported 47 · 6.2%Very low 212 · 27.7%Low 194 · 25.4%Moderate 99 · 13%High 18 · 2.4%

Intrauterine infusion/injection of autologous platelet‐rich plasma vs placebo or no intervention

Adverse events: ectopic pregnancy · women undergoing assisted reproduction

It is very uncertain whether intrauterine infusion/injection of autologous platelet‐rich plasma changes adverse events: ectopic pregnancy compared with no intervention or placebo (very low certainty).

1 finding from 1 review

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

Postoperative pain or distress · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

Participant satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

Intraoperative or postoperative bleeding · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

Physiological parameters (cardiac/respiratory events; type and volume of GA drug) · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

Parental satisfaction · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

Lip or cheek biting, numbness or allergy · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…

The review found no eligible studies for this question.

1 finding from 1 review

Infiltration injection LA and intraligamental injection LA (3-arm) vs no treatment

Postoperative anxiety · Children and young people aged 17 years or younger having dental treatment (including extractions) under general anaesthesia (secondary…
1 finding from 1 review

Live zoster vaccine vs placebo

Participants with adverse events ‐ injection site adverse events Clinical criteria · healthy older adults aged ≥ 60 years

Live zoster vaccine probably leads to higher participants with adverse events ‐ injection site adverse… compared with placebo (moderate certainty).

1 finding from 1 review

Low molecular weight heparin vs no prophylaxis

All adverse effects, including allergies at injection site, minor and major bleeding, others ( · adults undergoing KA

Low‐molecular‐weight heparin showed no clear difference in all adverse effects, including allergies at injection site, minor… compared with no prophylaxis (moderate certainty).

1 finding from 1 review

Intratympanic plus systemic corticosteroids (combined therapy) vs systemic corticosteroids alone

Vertigo/dizziness: at the time of injection · sudden sensorineural hearing loss
2 findings from 1 review

Intratympanic plus systemic corticosteroids (combined therapy) vs systemic corticosteroids alone

Ear pain: at the time of injection · sudden sensorineural hearing loss
2 findings from 1 review