Neurodevelopmental outcomes · preterm infants with apnea
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Failed CPAP · preterm infants with apnea
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Mean apnoea events · preterm infants with apnea
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found
Intervention not reported
Need for surgical closure of PDA (during hospital stay) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
The intervention probably leads to lower need for surgical closure of PDA (during hospital stay) (moderate certainty).
1 finding from 1 review
Intervention not reported
IVH grade III to IV (during hospital stay) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
The intervention showed no clear difference in IVH grade III to IV (during hospital stay) (moderate certainty).
1 finding from 1 review
Intervention not reported
NEC (during hospital stay) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
The intervention showed no clear difference in NEC (during hospital stay) (moderate certainty).
1 finding from 1 review
Intervention not reported
Gastrointestinal haemorrhage (during hospital stay) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
The intervention may leads to higher gastrointestinal haemorrhage (during hospital stay) (low certainty).
1 finding from 1 review
Intervention not reported
Oliguria (during ibuprofen treatment) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
The intervention leads to higher oliguria (during ibuprofen treatment) (high certainty).
1 finding from 1 review
Intervention not reported
Serum creatinine levels (mg/dL) (after treatment) Normal values for male and female newborns (17.7 to 88.4 µmol/L) (0.23 to 1.16 mg/dL) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
1 finding from 1 review
Intervention not reported
Gastrointestinal haemorrhage (during hospital stay) · preterm or low birth weight infants with risk of having PDA on day 3 to 4 of life
The intervention may leads to higher gastrointestinal haemorrhage (during hospital stay) (low certainty).
1 finding from 1 review
Neonatal mortality · neonates with possible serious bacterial infection
Comparison 2: any simplified antibiotic regimen showed no clear difference in neonatal mortality compared with the standard antibiotic regimen (7 days injectable benzylpenicillin… (moderate certainty).
1 finding from 1 review
Treatment failure · neonates with possible serious bacterial infection
Comparison 2: any simplified antibiotic regimen showed no clear difference in treatment failure compared with the standard antibiotic regimen (7 days injectable benzylpenicillin… (moderate certainty).
1 finding from 1 review
Adverse events · neonates with possible serious bacterial infection
Comparison 2: any simplified antibiotic regimen showed no clear difference in adverse events compared with the standard antibiotic regimen (7 days injectable benzylpenicillin… (moderate certainty).
1 finding from 1 review
Intervention not reported
Motor development and vigor (MDV) domain of the NAPI tool Normative mean and SD at 36 weeks PMA 63 (14.5) Higher scores are associated with more mature behaviour (Snider 2005) · neonates with pain associated with potentially painful procedures for 7 days
1 finding from 1 review
Intervention not reported
Alertness and orientation (AO) domain of the NAPI tool Normative mean and SD at 36 weeks PMA 54 (19.4) Higher scores are associated with more mature behaviour (Snider 2005) · neonates with pain associated with potentially painful procedures for 7 days
1 finding from 1 review
Combined outcome of mortality or BPD at 36 weeks' PMA · preterm infants
It is very uncertain whether inhaled corticosteroids changes combined outcome of mortality or BPD at 36 weeks' PMA compared with placebo (very low certainty).
1 finding from 1 review
Mortality at 36 weeks' PMA · preterm infants
It is very uncertain whether inhaled corticosteroids changes mortality at 36 weeks' PMA compared with placebo (very low certainty).
1 finding from 1 review
Bronchopulmonary dysplasia/chronic lung disease · preterm infants
It is very uncertain whether inhaled corticosteroids changes BPD at 36 weeks' PMA compared with placebo (very low certainty).
1 finding from 1 review
Open‐label use of systemic corticosteroids · preterm infants
It is very uncertain whether inhaled corticosteroids changes open‐label use of systemic corticosteroids compared with placebo (very low certainty).
1 finding from 1 review
Mortality Mortality at latest · preterm infants with chronic lung disease
Systemic corticosteroids (dexamethasone or hydrocortisone) leads to lower mortality at latest reported age compared with control (placebo or nothing) (high certainty).
1 finding from 1 review