Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

339 questions · 346 findings · 42 reviews · Headline outcomes only

No studies found 74 · 21.4%GRADE not reported 8 · 2.3%Very low 72 · 20.8%Low 107 · 30.9%Moderate 68 · 19.7%High 17 · 4.9%

Nimodipine vs placebo

Death at the end of · people with acute ischemic stroke

Nimodipine showed no clear difference in death at the end of compared with placebo (moderate certainty).

1 finding from 1 review

Nimodipine vs placebo

Recurrence of stroke at the end of · people with acute ischemic stroke

Nimodipine showed no clear difference in recurrence of stroke at the end of compared with placebo (moderate certainty).

1 finding from 1 review

Nimodipine vs placebo

Adverse events during treatment period · people with acute ischemic stroke

Nimodipine showed no clear difference in adverse events during treatment period compared with placebo (moderate certainty).

1 finding from 1 review

Nimodipine vs placebo

Hypotension · people with acute ischemic stroke

Nimodipine showed no clear difference in hypotension during treatment period compared with placebo (moderate certainty).

1 finding from 1 review

Nimodipine vs placebo

Systolic blood pressure · people with acute ischemic stroke

Nimodipine showed no clear difference in mean systolic blood pressure during or at end of treatment compared with placebo (low certainty).

1 finding from 1 review

Flunarizine vs placebo

Death or dependency at end of · people with acute ischemic stroke

Flunarizine showed no clear difference in death or dependency at end of compared with placebo (low certainty).

1 finding from 1 review

Flunarizine vs placebo

Death at the end of treatment · people with acute ischemic stroke

Flunarizine showed no clear difference in death at the end of treatment compared with placebo (low certainty).

1 finding from 1 review