Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

313 questions · 319 findings · 81 reviews

No studies found 97 · 30.4%GRADE not reported 20 · 6.3%Very low 98 · 30.7%Low 66 · 20.7%Moderate 32 · 10%High 6 · 1.9%

PERPHENAZINE vs antipsychotics

Service use and hospitalisation: admission ‐ not reported · patients with schizophrenia

The review found no eligible studies for this question.

1 finding from 1 review

PERPHENAZINE vs antipsychotics

Global state: Change over time ‐ no better or deterioration ‐ short and medium term as defined in each study · patients with schizophrenia

It is very uncertain whether PERPHENAZINE changes global state: Change over time ‐ no better or deterioration ‐ short… compared with ANY ANTIPSYCHOTICS (very low certainty).

1 finding from 1 review

PERPHENAZINE vs antipsychotics

Mental state: State ‐ 'no effect' BPRS score reduction · patients with schizophrenia

It is very uncertain whether PERPHENAZINE changes mental state: State ‐ 'no effect' BPRS score reduction compared with ANY ANTIPSYCHOTICS (very low certainty).

1 finding from 1 review

Antibiotics vs control

Active trachoma · people (any age) with active trachoma

Antibiotic may leads to lower active trachoma Clinical assessment: active trachoma defined as TF,… compared with control (low certainty).

1 finding from 1 review

Oral azithromycin vs control

Ocular chlamydia trachomatis infection · people (any age) with active trachoma

The review found no eligible studies for this question.

1 finding from 1 review
  • Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
    no estimate extracted
    Studies not reported
    No studies found

Oral azithromycin vs control

Antibiotic resistance · people (any age) with active trachoma

Oral azithromycin led to lower antibiotic resistance Proportion of samples showing evidence of… compared with control; GRADE not reported.

1 finding from 1 review
  • Antibiotics for trachoma 2019 · Cochrane Headline outcomes only
    no estimate extracted
    4 studies · 1354 participants
    GRADE not reported

Antibiotics vs control

Ocular chlamydia trachomatis infection · people (any age) with active trachoma

Antibiotic showed no clear difference in ocular C trachomatis infection Positive test for C trachomatis… compared with control (low certainty).

1 finding from 1 review