Success of surgery (eruption of the canine crown sufficient for orthodontic alignment, without repeated surgery) · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)
Open surgical exposure showed no clear difference in success of surgery (eruption of the canine crown sufficient for… compared with closed surgical exposure (low certainty).
1 finding from 1 review
Adverse effects · Children and adolescents (general population, aged under 20 years)
1 finding from 1 review
Change in probing pocket depth (PPD) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
1 finding from 1 review
Dry mouth (xerostomia) · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
1 finding from 1 review
Nausea · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
Amifostine may leads to higher nausea (adverse effect) compared with no treatment/placebo (low certainty).
1 finding from 1 review
Probing pocket depth · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
Periodontal treatment (scaling and root planing, alone or with… led to lower probing depth compared with alternative (less intensive) periodontal treatment, alone or with…; GRADE not reported.
1 finding from 1 review
Periodontal/peri-implant status and occlusal wear (secondary outcomes) · Adults (18 years or older) needing a three-unit fixed dental prosthesis (FDP)
The review found no eligible studies for this question.
1 finding from 1 review
Side effects · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
1 finding from 1 review
Low rates of adverse effects (watering eyes, nervousness, frequent urination, sweating, warm face, cramps, diarrhoea, nausea) with insufficient evidence of any differences (Jham 2007)
1 study
GRADE not reported
Quality of life and other oral related symptoms · Patients receiving radiotherapy on its own or in addition to chemotherapy to the head and neck region
1 finding from 1 review
Insufficient evidence of a difference for global quality of life, mouth pain RR 0.94 (95% CI 0.66 to 1.33), sore/burning mouth RR 0.95 (95% CI 0.68 to 1.35), throat pain RR 0.79 (95% CI 0.56 to 1.12) (Duncan 2005)
1 study
GRADE not reported
Treatment time: length of time in the operating theatre (first incision to final suture) · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)
It is very uncertain whether open surgical exposure changes treatment time: length of time in the operating theatre (first… compared with closed surgical exposure (very low certainty).
1 finding from 1 review
Taste acuity improvement - objective outcome (continuous data) · Patients with taste disturbances (dysgeusia/hypogeusia; idiopathic, zinc-deficient, or secondary to chronic renal failure)
It is very uncertain whether zinc supplements (zinc sulphate, zinc gluconate, zinc picolinate,… changes taste acuity improvement - objective outcome (continuous data) compared with placebo (very low certainty).
1 finding from 1 review
Restoration failure (permanent dentition) · People with dental caries in primary teeth (mainly children)
The review found no eligible studies for this question.
1 finding from 1 review
Oral mucositis (moderate to severe) · Adults with cancer receiving treatment
It is very uncertain whether granulocyte-colony stimulating factor (G-CSF) changes oral mucositis (moderate to severe) compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Gum health: radiographic crestal bone level · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)
Open surgical exposure showed no clear difference in gum health: radiographic crestal bone level compared with closed surgical exposure; GRADE not reported.
1 finding from 1 review
Costs (direct and indirect) · Children with carious primary teeth
The review found no eligible studies for this question.
1 finding from 1 review
Small‐for‐gestational age · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
Periodontal treatment (scaling and root planing, polishing, or… showed no clear difference in small for gestational age compared with no treatment (low certainty).
1 finding from 1 review
Oral mucositis (any severity) · Adults receiving bone marrow/stem cell transplantation after conditioning therapy for haematological cancers
Erythropoietin mouthwash led to lower oral mucositis (any severity) compared with placebo; GRADE not reported.
1 finding from 1 review
Patient satisfaction (measured by patient satisfaction or aesthetic scales) · Adults (18 years or older) needing a three-unit fixed dental prosthesis (FDP)
It is very uncertain whether metal-free FDPs (zirconia ceramic) changes aesthetic evaluation (patient aesthetic satisfaction changes) compared with metal-ceramic FDPs (very low certainty).
1 finding from 1 review
Interruptions to cancer treatment (radiotherapy breaks longer than two days) · Adults with cancer receiving treatment
Epidermal growth factor (EGF), oral spray showed no clear difference in interruptions to cancer treatment (radiotherapy breaks longer than… compared with placebo; GRADE not reported.
1 finding from 1 review
Failure to complete orthodontic treatment due to pain · People undergoing orthodontic treatment (any age; 9 to 34 years in included studies)
The review found no eligible studies for this question.
1 finding from 1 review