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What do systematic reviews say?

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Evidence found and GRADE certainty

4,678 questions · 4,859 findings · 283 reviews

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No studies found 1,225 · 25.2%GRADE not reported 215 · 4.4%Very low 1,241 · 25.5%Low 1,210 · 24.9%Moderate 776 · 16%High 192 · 4%

Psychological interventions vs psychological treatment

Depression remission · health problem or population

Summary of findings table ‐ Psychological treatment 1 showed no clear difference in depression remission ‐ short term (end of treatment) compared with psychological treatment 2 (low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Antithrombin concentrates vs no antithrombin concentrates

Death Analysis 1.1 · adults with acute lymphoblastic leukaemia treated with asparaginase‐based chemotherapy

It is very uncertain whether summary of Findings Table ‐ Antithrombin concentrates changes all‐cause mortality ‐ Intention‐to‐treat analysis compared with no antithrombin concentrates (very low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Antithrombin concentrates vs no antithrombin concentrates

Venous thromboembolism‐related mortality ‐ Intention‐to‐treat analysis · adults with acute lymphoblastic leukaemia treated with asparaginase‐based chemotherapy

It is very uncertain whether summary of Findings Table ‐ Antithrombin concentrates changes venous thromboembolism‐related mortality ‐ Intention‐to‐treat analysis compared with no antithrombin concentrates (very low certainty).

1 finding from 1 review

Summary of Findings Table ‐ Antithrombin concentrates vs no antithrombin concentrates

Clinically relevant non‐major bleeding ‐ not reported · adults with acute lymphoblastic leukaemia treated with asparaginase‐based chemotherapy

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings: balance and functional exercises vs control (e.g. usual activities)

Number of people sustaining one or more fall‐related fractures · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

Summary of findings: balance and functional exercises may leads to lower number of people who experienced one or more fall‐related fractures. compared with control (e.g. usual activities) (low certainty).

1 finding from 1 review

Summary of findings: balance and functional exercises vs control (e.g. usual activities)

Falls · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

Summary of findings: balance and functional exercises leads to lower rate of falls (falls per person‐years) compared with control (e.g. usual activities) (high certainty).

1 finding from 1 review

Summary of findings: balance and functional exercises vs control (e.g. usual activities)

Number of people who experienced one or more falls · Older people living in the community (trials focusing on people recently discharged from hospital were not included)

Summary of findings: balance and functional exercises leads to lower number of people who experienced one of more falls compared with control (e.g. usual activities) (high certainty).

1 finding from 1 review

Summary of findings for multi‐dose nasal decongestant vs placebo

Primary outcome: subjective symptom score (mean) ‐ 3 hours after dosing · adult patients with the common cold
3 findings from 1 review