Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,320 questions · 4,561 findings · 388 reviews

No studies found 1,138 · 25%GRADE not reported 886 · 19.4%Very low 1,014 · 22.2%Low 849 · 18.6%Moderate 543 · 11.9%High 131 · 2.9%

Live attenuated influenza vaccine vs placebo or no intervention

Influenza assessed by laboratory confirmation · healthy, community‐dwelling children younger than 16 years of age

Live attenuated influenza vaccine probably leads to lower influenza assessed by laboratory confirmation compared with placebo or do nothing (moderate certainty).

1 finding from 1 review

Live attenuated influenza vaccine vs placebo or no intervention

Otitis media · healthy, community‐dwelling children younger than 16 years of age

Live attenuated influenza vaccine showed no clear difference in otitis media assessed by clinical confirmation (inspection of ear… compared with placebo or do nothing (moderate certainty).

1 finding from 1 review

Live attenuated influenza vaccine vs placebo or no intervention

Number of children with time off from school during · healthy, community‐dwelling children younger than 16 years of age

It is very uncertain whether live attenuated influenza vaccine changes number of children with time off from school during compared with placebo or do nothing (very low certainty).

1 finding from 1 review

Live attenuated influenza vaccine vs placebo or no intervention

Number of parents having to take off work during · healthy, community‐dwelling children younger than 16 years of age

Live attenuated influenza vaccine showed no clear difference in number of parents having to take off work during compared with placebo or do nothing (low certainty).

1 finding from 1 review