Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,584 questions · 3,695 findings · 567 reviews

No studies found 784 · 21.2%GRADE not reported 308 · 8.3%Very low 1,036 · 28%Low 971 · 26.3%Moderate 440 · 11.9%High 156 · 4.2%

Custom foot orthoses vs shoes

Pain (measured as proportion with pain) · children with asymptomatic flat feet

Customised foot orthoses showed no clear difference in pain (measured as proportion with pain) compared with shoes (low certainty).

1 finding from 1 review

Custom foot orthoses vs shoes

Withdrawals due to adverse events · children with juvenile idiopathic arthritis and flat feet

Custom foot orthoses showed no clear difference in withdrawal due to adverse events compared with shoes (low certainty).

1 finding from 1 review

CarieScan Pro device vs Reference standard (histology, excavation, or enhanced visual examination)

Sensitivity · Children, adolescents, or adults presenting asymptomatically or suspected of early enamel caries (in vivo), or extracted teeth of…
1 finding from 1 review
  • Electrical conductance for the detection of dental caries 2021 · Cochrane All outcomes
    Up to 3 months between index test and reference standard (in vivo studies)
    CarieScan Pro (3 studies, 244 tooth surfaces): sensitivity ranged from 0.55 to 0.91. No evidence of a difference in accuracy by device type (Chi2=0.05, df=1, P=0.82).
    3 studies
    GRADE not reported