Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,018 questions · 3,100 findings · 369 reviews · Headline outcomes only

No studies found 774 · 25%GRADE not reported 108 · 3.5%Very low 727 · 23.5%Low 840 · 27.1%Moderate 474 · 15.3%High 177 · 5.7%

Intervention not reported

Overall survival (surviving rates) · patients with resectable disease

The intervention showed no clear difference in overall survival (surviving rates) (low certainty).

1 finding from 1 review

Intervention not reported

Disease specific survival (surviving rates) · patients with resectable disease

The intervention probably leads to lower disease specific survival (surviving rates) (moderate certainty).

1 finding from 1 review

Intervention not reported

Disease free survival (surviving rates) · patients with resectable disease

The intervention showed no clear difference in disease free survival (surviving rates) (moderate certainty).

1 finding from 1 review

Intervention not reported

Postoperative mortality (within 30 days from surgery) · patients with resectable disease

The intervention leads to higher postoperative mortality (within 30 days from surgery) (high certainty).

1 finding from 1 review

Intervention not reported

Mortality · Treating bleeding trauma patients

The intervention leads to lower mortality (high certainty).

1 finding from 1 review

Intervention not reported

Progressive intracranial haemorrhage · Treating patients with traumatic brain injury

The intervention leads to lower progressive intracranial haemorrhage (high certainty).

1 finding from 1 review

Intervention not reported

New brain lesions · Treating patients with traumatic brain injury

The intervention showed no clear difference in new brain lesions (moderate certainty).

1 finding from 1 review

Intervention not reported

Myocardial infarction · Treating patients with traumatic brain injury

The intervention showed no clear difference in myocardial infarction (low certainty).

1 finding from 1 review

Intervention not reported

Stroke · Treating patients with traumatic brain injury

The intervention showed no clear difference in stroke (low certainty).

1 finding from 1 review

Intervention not reported

Deep vein thrombosis · Treating patients with traumatic brain injury

The intervention showed no clear difference in deep vein thrombosis (low certainty).

1 finding from 1 review

Intervention not reported

Surgical intervention · Treating bleeding trauma patients

The intervention showed no clear difference in surgical intervention (high certainty).

1 finding from 1 review

Intervention not reported

Blood transfusion · Treating bleeding trauma patients

The intervention showed no clear difference in blood transfusion (high certainty).

1 finding from 1 review

Intervention not reported

Myocardial infarction · Treating bleeding trauma patients

The intervention probably leads to lower myocardial infarction (moderate certainty).

1 finding from 1 review

Intervention not reported

Deep vein thrombosis · Treating bleeding trauma patients

The intervention showed no clear difference in deep vein thrombosis (moderate certainty).

1 finding from 1 review

Intervention not reported

Stroke · Treating bleeding trauma patients

The intervention showed no clear difference in stroke (moderate certainty).

1 finding from 1 review

Intervention not reported

Pulmonary embolism · Treating bleeding trauma patients

The intervention showed no clear difference in pulmonary embolism (moderate certainty).

1 finding from 1 review

Intervention not reported

Mortality · Treating patients with traumatic brain injury

The intervention may leads to lower mortality (low certainty).

1 finding from 1 review

Intervention not reported

Surgical intervention · Treating patients with traumatic brain injury

The intervention showed no clear difference in surgical intervention (low certainty).

1 finding from 1 review