Findings

What do systematic reviews say?

2,908 questions · 3,101 findings · 509 reviews

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No studies found 571 · 18.4%GRADE not reported 358 · 11.5%Very low 723 · 23.3%Low 854 · 27.5%Moderate 489 · 15.8%High 106 · 3.4%

Subgroup analysis: Exercise duration vs resistance

Pain ‐ resistance exercise WOMAC (VAS or Likert) from 0 to 20 · Patients with osteoarthritis of the knee or hip

1 finding from 1 review

High‐intensity versus low‐intensity physical activity or exercise in people with hip or knee osteoarthritis 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 113 participants
Very low

Subgroup analysis: Exercise duration vs resistance

Function ‐ duration exercise WOMAC from 0 to 68 · Patients with osteoarthritis of the knee or hip

1 finding from 1 review

High‐intensity versus low‐intensity physical activity or exercise in people with hip or knee osteoarthritis 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 200 participants
Very low

Subgroup analysis: Exercise duration vs resistance

Function ‐ resistance exercise WOMAC from 0 to 68 · Patients with osteoarthritis of the knee or hip

1 finding from 1 review

High‐intensity versus low‐intensity physical activity or exercise in people with hip or knee osteoarthritis 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 113 participants
Low

Intervention not reported

Total mortality Systolic targets · Diabetes Mellitus with elevated blood pressure

The intervention showed no clear difference in total mortality Systolic targets (low certainty).

1 finding from 1 review

Blood pressure targets for hypertension in people with diabetes mellitus 2013 · Cochrane Headline outcomes only
RR 1.05 [0.84, 1.3]
1 study · 4734 participants
Low

Intervention not reported

Total mortality Diastolic targets · Diabetes Mellitus with elevated blood pressure

It is very uncertain whether the intervention changes total mortality Diastolic targets (very low certainty).

1 finding from 1 review

Blood pressure targets for hypertension in people with diabetes mellitus 2013 · Cochrane Headline outcomes only
RR 0.73 [0.53, 1.01]
4 studies · 2580 participants
Very low

Intervention not reported

Total serious adverse events Systolic targets · Diabetes Mellitus with elevated blood pressure

The intervention showed no clear difference in total serious adverse events Systolic targets (low certainty).

1 finding from 1 review

Blood pressure targets for hypertension in people with diabetes mellitus 2013 · Cochrane Headline outcomes only
RR 1.01 [0.91, 1.13]
1 study · 4734 participants
Low

Intervention not reported

Creatine phosphate 1g/day · patients with heart failure

1 finding from 1 review

Creatine and creatine analogues in hypertension and cardiovascular disease 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 13 participants
Low

Intervention not reported

Creatine 20g/day for 6 weeks · patients with heart failure

1 finding from 1 review

Creatine and creatine analogues in hypertension and cardiovascular disease 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 13 participants
Low

Intervention not reported

Creatine 20g/day for 10 days · patients with heart failure

1 finding from 1 review

Creatine and creatine analogues in hypertension and cardiovascular disease 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 17 participants
Low

Intervention not reported

Creatinine phosphate 1g/day for 6 months · patients with heart failure

1 finding from 1 review

Creatine and creatine analogues in hypertension and cardiovascular disease 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 79 participants
Low

Intervention not reported

Creatinine phosphate 1g/day for 3 months · patients with heart failure

1 finding from 1 review

Creatine and creatine analogues in hypertension and cardiovascular disease 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 88 participants
Low

Intervention not reported

Peak exercise capacity: Power (W) · people with chronic obstructive pulmonary disease

1 finding from 1 review

Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease 2011 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 367 participants
Moderate

Intervention not reported

Peak exercise capacity: Peak oxygen consumption (VO2peak) (L/min) · people with chronic obstructive pulmonary disease

1 finding from 1 review

Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease 2011 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 188 participants
Moderate

Intervention not reported

Peak exercise test: Lactate threshold (L/min) · people with chronic obstructive pulmonary disease

1 finding from 1 review

Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease 2011 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 94 participants
Moderate

Intervention not reported

Peak exercise test: Isowork minute ventilation (VE) (L) · people with chronic obstructive pulmonary disease

1 finding from 1 review

Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease 2011 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 77 participants
Low

Intervention not reported

Peak exercise test: Isowork dyspnoea score · people with chronic obstructive pulmonary disease

1 finding from 1 review

Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
Low

Intervention not reported

Exercise tolerance: Endurance time (min) · people with chronic obstructive pulmonary disease

1 finding from 1 review

Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease 2011 · Cochrane Headline outcomes only
no estimate extracted
1 study · 41 participants
Low

Intervention not reported

Functional exercise capacity: Six‐minute walk distance (m) · people with chronic obstructive pulmonary disease

1 finding from 1 review

Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease 2011 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 287 participants
Low

Intervention not reported

Health‐related Quality of Life: Dyspnoea domain of the CRQ · people with chronic obstructive pulmonary disease

1 finding from 1 review

Optimal intensity and type of leg exercise training for people with chronic obstructive pulmonary disease 2011 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 212 participants
Moderate

Calcium channel blockers vs placebo/no treatment

Death · kidney transplant recipients

Calcium channel blockers showed no clear difference in death compared with placebo/no treatment (low certainty).

1 finding from 1 review

Antihypertensive treatment for kidney transplant recipients 2009 · Cochrane Headline outcomes only
RR 0.82 [0.37, 1.82]
12 studies · 792 participants
Low