Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,535 questions · 3,601 findings · 252 reviews · Pregnancy and Childbirth

No studies found 726 · 20.2%GRADE not reported 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Corticosteroids vs placebo

Pregnancy complications · Pregnant women with hyperemesis gravidarum

It is very uncertain whether corticosteroids changes pregnancy complications compared with placebo (very low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Spontaneous abortion · Pregnant women with hyperemesis gravidarum

It is very uncertain whether corticosteroids changes spontaneous abortion compared with placebo (very low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Perinatal mortality · Pregnant women with hyperemesis gravidarum

It is very uncertain whether corticosteroids changes stillbirth and neonatal death compared with placebo (very low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Congenital abnormalities · Pregnant women with hyperemesis gravidarum

It is very uncertain whether corticosteroids changes congenital abnormalities compared with placebo (very low certainty).

1 finding from 1 review

Corticosteroids vs placebo

Severity, reduction or cessation in nausea/vomiting 2. Number of episodes of emesis 3. Quality of life outcomes · Pregnant women with hyperemesis gravidarum

The review found no eligible studies for this question.

1 finding from 1 review

Acupuncture vs metoclopramide

Reduction or cessation in nausea · Pregnant women with hyperemesis gravidarum

It is very uncertain whether acupuncture changes reduction or cessation in nausea compared with metoclopramide (very low certainty).

1 finding from 1 review

Acupuncture vs metoclopramide

Reduction or cessation in vomiting · Pregnant women with hyperemesis gravidarum

It is very uncertain whether acupuncture changes reduction or cessation in vomiting compared with metoclopramide (very low certainty).

1 finding from 1 review

Summary of findings ‐ Nipple stimulation (suckling) vs no treatment (comparison 1)

Maternal death · nipple stimulation (suckling) for preventing postpartum haemorrhage in the third stage of labour.

It is very uncertain whether summary of findings ‐ Nipple stimulation (suckling) changes maternal death compared with no treatment (comparison 1) (very low certainty).

1 finding from 1 review

Summary of findings ‐ Nipple stimulation (suckling) vs no treatment (comparison 1)

Frequency of PPH ≥ 500 mL · nipple stimulation (suckling) for preventing postpartum haemorrhage in the third stage of labour.

Summary of findings ‐ Nipple stimulation (suckling) showed no clear difference in frequency of PPH ≥ 500 mL compared with no treatment (comparison 1) (moderate certainty).

1 finding from 1 review

Summary of findings ‐ Nipple stimulation (suckling) vs no treatment (comparison 1)

Retained placenta · nipple stimulation (suckling) for preventing postpartum haemorrhage in the third stage of labour.

It is very uncertain whether summary of findings ‐ Nipple stimulation (suckling) changes retained placenta compared with no treatment (comparison 1) (very low certainty).

1 finding from 1 review

Summary of findings ‐ Nipple stimulation (suckling) vs no treatment (comparison 1)

Perinatal mortality · nipple stimulation (suckling) for preventing postpartum haemorrhage in the third stage of labour.

Summary of findings ‐ Nipple stimulation (suckling) showed no clear difference in perinatal death compared with no treatment (comparison 1) (low certainty).

1 finding from 1 review

Summary of findings ‐ Nipple stimulation (suckling) vs no treatment (comparison 1)

Maternal admission to hospital · nipple stimulation (suckling) for preventing postpartum haemorrhage in the third stage of labour.

It is very uncertain whether summary of findings ‐ Nipple stimulation (suckling) changes maternal admission to hospital compared with no treatment (comparison 1) (very low certainty).

1 finding from 1 review