Other congenital anomalies (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
Supplementation with folate showed no clear difference in other congenital anomalies (All) compared with no intervention, placebo or other micronutrients without folate… (low certainty).
1 finding from 1 review
Neonatal mortality · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
1 finding from 1 review
Maternal anaemia at or near term (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
1 finding from 1 review
Maternal red blood cell folate at or near term (All) · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
1 finding from 1 review
Serum folate at or near term · all women who become pregnant or were 12 or less weeks' pregnant at the time of the intervention
1 finding from 1 review
Low birthweight · Women receiving supplements in pregnancy
Any intermittent iron regimen (with or without other vitamins and… showed no clear difference in low birthweight (less than 2500 g) compared with daily regimen (with same vitamins and minerals)‐infant outcomes (low certainty).
1 finding from 1 review
Participants with at least some Side Effects · Women receiving supplements in pregnancy
It is very uncertain whether any intermittent iron regimen (with or without other vitamins and… changes side effects (any reported throughout intervention period) compared with daily regimen (with same vitamins and minerals)‐maternal outcomes (very low certainty).
1 finding from 1 review
Severe anaemia at any time during second and third trimester (Hb less than 70 g/L) · Women receiving supplements in pregnancy
1 finding from 1 review
Maternal clinical malaria or other infection in pregnancy · Women receiving supplements in pregnancy
Any intermittent iron regimen (with or without other vitamins and… led to lower maternal clinical malaria or other infection in pregnancy compared with daily regimen (with same vitamins and minerals)‐maternal outcomes; GRADE not reported.
1 finding from 1 review
Birthweight (g) · Women receiving supplements in pregnancy
Any intermittent iron regimen (with or without other vitamins and… showed no clear difference in birthweight (g) compared with daily regimen (with same vitamins and minerals)‐infant outcomes (low certainty).
1 finding from 1 review
Gestational age (preterm birth < 37 weeks) · Women receiving supplements in pregnancy
Any intermittent iron regimen (with or without other vitamins and… showed no clear difference in premature birth (less than 37 weeks of gestation) compared with daily regimen (with same vitamins and minerals)‐infant outcomes (low certainty).
1 finding from 1 review
Neonatal mortality · Women receiving supplements in pregnancy
It is very uncertain whether any intermittent iron regimen (with or without other vitamins and… changes neonatal death (within 28 days after delivery) compared with daily regimen (with same vitamins and minerals)‐infant outcomes (very low certainty).
1 finding from 1 review
Congenital anomalies (including neural tube defects) · Women receiving supplements in pregnancy
1 finding from 1 review
Maternal anaemia at term (Hb less than 110 g/L at 37 weeks' gestation or more) (ALL) · Women receiving supplements in pregnancy
It is very uncertain whether any intermittent iron regimen (with or without other vitamins and… changes maternal anaemia at term (Hb less than 110 g/L at 37 weeks'… compared with daily regimen (with same vitamins and minerals)‐maternal outcomes (very low certainty).
1 finding from 1 review
Iron deficiency at term (as defined by trialists, based on any indicator of iron status at 37 wk gestation or more) · Women receiving supplements in pregnancy
1 finding from 1 review
Maternal iron‐deficiency anaemia at term (Hb less than 110 g/L and at least 1 additional laboratory indicators at 37 weeks' gestation or more) · Women receiving supplements in pregnancy
It is very uncertain whether any intermittent iron regimen (with or without other vitamins and… changes maternal iron‐deficiency anaemia at term (Hb less than 110 g/L and… compared with daily regimen (with same vitamins and minerals)‐maternal outcomes (very low certainty).
1 finding from 1 review
Maternal death · Women receiving supplements in pregnancy
Any intermittent iron regimen (with or without other vitamins and… led to lower maternal death (death while pregnant or within 42 days of… compared with daily regimen (with same vitamins and minerals)‐maternal outcomes; GRADE not reported.
1 finding from 1 review
Intervention not reported
At least 50% of maximum pain relief over 4 to 6 h · adults with moderate or severe acute postoperative pain
The intervention leads to higher at least 50% of maximum pain relief over 4 to 6 h (high certainty).
1 finding from 1 review
RR 4.1 [2.8, 5.9]
Studies not reported
High
Intervention not reported
Participants with at least 1 adverse event · adults with moderate or severe acute postoperative pain
The intervention showed no clear difference in participants with at least 1 adverse event (moderate certainty).
1 finding from 1 review
RR 1.2 [0.84, 1.7]
Studies not reported
Moderate
Intervention not reported
Participants with a serious adverse event · adults with moderate or severe acute postoperative pain
The review found no eligible studies for this question.
1 finding from 1 review
no estimate extracted
Studies not reported
No studies found