Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

4,587 questions · 5,761 findings · 495 reviews

No studies found 1,011 · 17.5%GRADE not reported 1,797 · 31.2%Very low 1,100 · 19.1%Low 1,052 · 18.3%Moderate 649 · 11.3%High 152 · 2.6%

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Monthly pulsed high‐dose dexamethasone vs prednisolone

≥ 1 point improvement on INCAT disability score at 12 months · patients with chronic inflammatory demyelinating polyradiculoneuropathy

Monthly pulsed high‐dose dexamethasone may leads to higher ≥ 1 point improvement on INCAT disability score at 12 months compared with oral prednisolone (low certainty).

1 finding from 1 review

Intervention not reported

Seizure freedom (1‐ to 3‐month blinded evaluation periods) · patients with refractory medial temporal lobe epilepsy

The intervention showed no clear difference in seizure freedom (1‐ to 3‐month blinded evaluation periods) (moderate certainty).

1 finding from 1 review

Intervention not reported

Responder rate (1‐ to 3‐month blinded evaluation periods) · patients with refractory medial temporal lobe epilepsy

The intervention showed no clear difference in responder rate (1‐ to 3‐month blinded evaluation periods) (low certainty).

1 finding from 1 review

Intervention not reported

Seizure frequency (1‐ to 3‐month blinded evaluation periods) · patients with refractory medial temporal lobe epilepsy
1 finding from 1 review

Intervention not reported

Adverse events · patients with refractory medial temporal lobe epilepsy
1 finding from 1 review

Intervention not reported

Neuropsychological outcome (1‐ to 3‐month periods) · patients with refractory medial temporal lobe epilepsy
1 finding from 1 review

Intervention not reported

Quality of life (QOLIE‐89) (1‐ to 3‐month periods) · patients with refractory medial temporal lobe epilepsy
1 finding from 1 review