What do systematic reviews say?

Metoclopramide vs promethazine

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 149 participants
  Low

Metoclopramide vs promethazine

Metoclopramide probably leads to lower intervention side effects: drowsy compared with promethazine (moderate certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.7 [0.56, 0.87]
  1 study · 143 participants
  Moderate

Metoclopramide vs promethazine

Metoclopramide showed no clear difference in intervention side effects: unable to sleep compared with promethazine (low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.78 [0.4, 1.53]
  1 study · 143 participants
  Low

Metoclopramide vs promethazine

Metoclopramide showed no clear difference in intervention side effects: dry mouth compared with promethazine (low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.91 [0.62, 1.34]
  1 study · 143 participants
  Low

Metoclopramide vs promethazine

Metoclopramide probably leads to lower intervention side effects: felt dizzy compared with promethazine (moderate certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.48 [0.34, 0.69]
  1 study · 143 participants
  Moderate

Acupuncture vs placebo

Acupuncture showed no clear difference in preterm birth less than 37 weeks compared with placebo (low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.12 [0.01, 2.26]
  1 study · 36 participants
  Low

Metoclopramide vs promethazine

Metoclopramide showed no clear difference in intervention side effects: diarrhea compared with promethazine (low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 1.39 [0.32, 5.99]
  1 study · 143 participants
  Low

Metoclopramide vs promethazine

Metoclopramide showed no clear difference in intervention side effects: headache compared with promethazine (low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.81 [0.47, 1.38]
  1 study · 143 participants
  Low

Metoclopramide vs promethazine

The review found no eligible studies for this question.

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Ondansetron vs promethazine

It is very uncertain whether ondansetron changes days of hospital admission compared with promethazine (very low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 30 participants
  Very low

Ondansetron vs promethazine

Ondansetron may leads to lower intervention side effect: sedation compared with promethazine (low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.06 [0, 0.94]
  1 study · 30 participants
  Low

Ondansetron vs promethazine

The review found no eligible studies for this question.

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Corticosteroids vs promethazine

Corticosteroids may leads to higher severe nausea 48 hours compared with promethazine (low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 2 [1.08, 3.72]
  1 study · 80 participants
  Low

Corticosteroids vs promethazine

It is very uncertain whether corticosteroids changes severe nausea 17th day compared with promethazine (very low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.81 [0.58, 1.15]
  1 study · 78 participants
  Very low

Corticosteroids vs promethazine

It is very uncertain whether corticosteroids changes episodes of vomiting 48 hours compared with promethazine (very low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 3 [0.33, 27.63]
  1 study · 80 participants
  Very low
• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 1 [0.21, 4.65]
  1 study · 78 participants
  Very low

Acupuncture vs placebo

Acupuncture showed no clear difference in stillbirth and neonatal death compared with placebo (low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.57 [0.04, 8.3]
  1 study · 36 participants
  Low

Corticosteroids vs promethazine

Corticosteroids showed no clear difference in intervention side effects: drowsiness 48hrs and 3‐10 days compared with promethazine (low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 0.08 [0, 1.32]
  1 study · 80 participants
  Low

Corticosteroids vs promethazine

Corticosteroids showed no clear difference in stillbirth and neonatal death compared with promethazine (low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 3 [0.13, 69.52]
  1 study · 40 participants
  Low

Corticosteroids vs promethazine

Corticosteroids showed no clear difference in preterm birth compared with promethazine (low certainty).

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  RR 3 [0.13, 69.52]
  1 study · 40 participants
  Low

Corticosteroids vs promethazine

The review found no eligible studies for this question.

• Interventions for treating hyperemesis gravidarum 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found