Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3,535 questions · 3,601 findings · 252 reviews · Pregnancy and Childbirth

No studies found 726 · 20.2%GRADE not reported 421 · 11.7%Very low 828 · 23%Low 993 · 27.6%Moderate 486 · 13.5%High 147 · 4.1%

Acupuncture vs placebo

Quality of life: anxiodepressive symptomatology · Pregnant women with hyperemesis gravidarum

It is very uncertain whether acupuncture changes quality of life: anxiodepressive symptomatology compared with placebo (very low certainty).

1 finding from 1 review

Pyridoxine vs placebo

Dizziness · Pregnant women with hyperemesis gravidarum

Pyridoxine showed no clear difference in interventions side effects: dizziness compared with placebo (low certainty).

1 finding from 1 review

Pyridoxine vs placebo

Adverse effects: headache · Pregnant women with hyperemesis gravidarum

Pyridoxine showed no clear difference in interventions side effects: headaches compared with placebo (low certainty).

1 finding from 1 review

Pyridoxine vs placebo

Interventions side effects: diarrhoea · Pregnant women with hyperemesis gravidarum

Pyridoxine showed no clear difference in interventions side effects: diarrhoea compared with placebo; GRADE not reported.

1 finding from 1 review

Pyridoxine vs placebo

Adverse effects: palpitations · Pregnant women with hyperemesis gravidarum

Pyridoxine showed no clear difference in interventions side effects: palpitations compared with placebo (low certainty).

1 finding from 1 review

Pyridoxine vs placebo

Adverse effects: dry mouth · Pregnant women with hyperemesis gravidarum

Pyridoxine showed no clear difference in interventions side effects: dry mouth compared with placebo (low certainty).

1 finding from 1 review

Pyridoxine vs placebo

Severity, reduction or cessation in nausea/vomiting 2. Quality of life outcomes 3. Pregnancy complications 4. Adverse fetal/neonatal outcomes · Pregnant women with hyperemesis gravidarum

The review found no eligible studies for this question.

1 finding from 1 review

Metoclopramide vs ondansetron

Intervention side effects: unable to sleep · Pregnant women with hyperemesis gravidarum

Metoclopramide showed no clear difference in intervention side effects: unable to sleep compared with ondansetron (low certainty).

1 finding from 1 review

Metoclopramide vs ondansetron

Adverse effects: dry mouth · Pregnant women with hyperemesis gravidarum

Metoclopramide probably leads to higher intervention side effects: dry mouth compared with ondansetron (moderate certainty).

1 finding from 1 review

Metoclopramide vs ondansetron

Frequency of adverse effects ‐ dizziness ( · Pregnant women with hyperemesis gravidarum

Metoclopramide showed no clear difference in intervention side effects: felt dizzy compared with ondansetron (low certainty).

1 finding from 1 review

Metoclopramide vs ondansetron

Severity, reduction or cessation in nausea/vomiting 2.Days of hospital admission 3. Pregnancy complications 4. Adverse fetal/neonatal outcomes · Pregnant women with hyperemesis gravidarum

The review found no eligible studies for this question.

1 finding from 1 review