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Search review questions

Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.

Limit to evidence status or GRADE (optional)

1,558 questions in 115 reviews · Vascular

current versions
No studies 346 · 22.2%Ungraded 90 · 5.8%Very low 281 · 18%Low 477 · 30.6%Moderate 313 · 20.1%High 51 · 3.3%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

QuestionEffectEvidenceStatus / GRADE
Laser plus sclerotherapy vs sclerotherapy
Resolution or improvement of telangiectasias ( · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
no estimate extracted2 studies · 710 participantsLow
Laser plus sclerotherapy vs sclerotherapy
Adverse events ‐ Hyperpigmentation ( · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
RR 0.83 [0.35, 1.99]2 studies · 656 participantsLow
Laser plus sclerotherapy vs sclerotherapy
Adverse events ‐ matting ( · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
RR 0.83 [0.21, 3.28]2 studies · 656 participantsLow
Laser plus sclerotherapy vs sclerotherapy
Pain ( · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
RR 2.44 [1.69, 3.55]1 study · 596 participantsLow
Laser plus sclerotherapy vs sclerotherapy
Recurrence · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
no estimate extractedNRNo studies
Laser plus sclerotherapy vs sclerotherapy
Time to resolution · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
no estimate extractedNRNo studies
Laser plus sclerotherapy vs sclerotherapy
Quality of life · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
no estimate extractedNRNo studies
Sclerotherapy (hypertonic glucose plus polidocanol) vs sclerotherapy (hypertonic glucose)
Resolution or improvement of telangiectasias ( · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
no estimate extracted2 studies · 191 participantsModerate
Sclerotherapy (hypertonic glucose plus polidocanol) vs sclerotherapy (hypertonic glucose)
Adverse events ‐ hyperpigmentation ( · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
RR 0.79 [0.62, 1.01]2 studies · 191 participantsModerate
Sclerotherapy (hypertonic glucose plus polidocanol) vs sclerotherapy (hypertonic glucose)
Adverse events ‐ matting ( · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
RR 0.78 [0.51, 1.2]2 studies · 191 participantsModerate
Sclerotherapy vs placebo
Time to resolution · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
no estimate extractedNRNo studies
Sclerotherapy (hypertonic glucose plus polidocanol) vs sclerotherapy (hypertonic glucose)
Pain ( · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
RR 1.02 [0.83, 1.24]2 studies · 191 participantsModerate
Sclerotherapy (hypertonic glucose plus polidocanol) vs sclerotherapy (hypertonic glucose)
Recurrence · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
no estimate extractedNRNo studies
Sclerotherapy (hypertonic glucose plus polidocanol) vs sclerotherapy (hypertonic glucose)
Time to resolution · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
no estimate extractedNRNo studies
Sclerotherapy (hypertonic glucose plus polidocanol) vs sclerotherapy (hypertonic glucose)
Quality of life · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
no estimate extractedNRNo studies
Sclerotherapy plus compression vs sclerotherapy alone
Resolution or improvement of telangiectasias ( · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
no estimate extracted2 studies · 196 participantsModerate
Sclerotherapy plus compression vs sclerotherapy alone
Adverse events ‐ hyperpigmentation ( · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
RR 0.93 [0.41, 2.07]2 studies · 196 participantsModerate
Sclerotherapy plus compression vs sclerotherapy alone
Adverse events ‐ matting ( · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
RR 1.84 [0.17, 19.62]1 study · 96 participantsLow
Sclerotherapy plus compression vs sclerotherapy alone
Pain · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
no estimate extractedNRNo studies
Sclerotherapy plus compression vs sclerotherapy alone
Recurrence · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
no estimate extractedNRNo studies
Sclerotherapy plus compression vs sclerotherapy alone
Time to resolution · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
no estimate extractedNRNo studies
Sclerotherapy vs placebo
Quality of life · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
no estimate extractedNRNo studies
Sclerotherapy plus compression vs sclerotherapy alone
Quality of life ( · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
no estimate extracted1 study · 93 participantsLow
Sclerotherapy (polidocanol) vs sclerotherapy (any sclerosant)
Resolution or improvement of telangiectasias ( · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
no estimate extracted7 studies · 852 participantsModerate
Sclerotherapy (polidocanol) vs sclerotherapy (any sclerosant)
Adverse events ‐ hyperpigmentation ( · people with telangiectasias and reticular veins
Treatment for telangiectasias and reticular veins (2021) · Cochrane
RR 0.94 [0.62, 1.43]6 studies · 819 participantsModerate
[Axillary] B‐mode ultrasound guidance vs palpation and landmarks
First‐attempt success rate · adults requiring axillary artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Dorsalis pedis] B‐mode ultrasound guidance vs palpation and landmarks
Overall success rate · adults requiring dorsalis pedis artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1 [0.91, 1.1]1 study · 60 participantsVery low
[Dorsalis pedis] B‐mode ultrasound guidance vs palpation and landmarks
Time needed for a successful procedure · adults requiring dorsalis pedis artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted1 study · 60 participantsVery low
[Dorsalis pedis] B‐mode ultrasound guidance vs palpation and landmarks
Major haematoma · adults requiring dorsalis pedis artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Dorsalis pedis] B‐mode ultrasound guidance vs palpation and landmarks
Adverse events (pain) · adults requiring dorsalis pedis artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Dorsalis pedis] B‐mode ultrasound guidance vs palpation and landmarks
Quality of life · adults requiring dorsalis pedis artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound guidance vs palpation and landmarks
First‐attempt success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.44 [1.29, 1.61]27 studies · 4708 participantsLow
[Radial] B‐mode ultrasound guidance vs palpation and landmarks
Pseudomaneurysm · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 2.89 [0.12, 70.63]1 study · 679 participantsVery low
[Radial] B‐mode ultrasound guidance vs palpation and landmarks
Overall success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.11 [1.06, 1.16]28 studies · 4955 participantsLow
[Radial] B‐mode ultrasound guidance vs palpation and landmarks
Time needed for a successful procedure · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted26 studies · 4902 participantsLow
[Radial] B‐mode ultrasound guidance vs palpation and landmarks
Major haematoma · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 0.35 [0.23, 0.56]16 studies · 2504 participantsModerate
[Axillary] B‐mode ultrasound guidance vs palpation and landmarks
Pseudoaneurysm · adults requiring axillary artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound guidance vs palpation and landmarks
Adverse events (pain) · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted4 studies · 883 participantsVery low
[Radial] B‐mode ultrasound guidance vs palpation and landmarks
Quality of life (satisfaction) · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted1 study · 72 participantsVery low
[Radial] B‐mode ultrasound vs Doppler assistance
First‐attempt success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.35 [1.11, 1.64]1 study · 493 participantsModerate
[Radial] B‐mode ultrasound vs Doppler assistance
Pseudoaneurysm · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound vs Doppler assistance
Overall success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.13 [0.99, 1.29]1 study · 493 participantsLow
[Radial] B‐mode ultrasound vs Doppler assistance
Time needed for a successful procedure · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extracted1 study · 493 participantsModerate
[Radial] B‐mode ultrasound vs Doppler assistance
Major haematoma · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound vs Doppler assistance
Adverse events (pain) · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound vs Doppler assistance
Quality of life · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound vs near‐infrared laser guidance
First‐attempt success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.33 [0.82, 2.16]1 study · 72 participantsVery low
[Axillary] B‐mode ultrasound guidance vs palpation and landmarks
Overall success rate · adults requiring axillary artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.35 [0.99, 1.86]1 study · 33 participantsVery low
[Radial] B‐mode ultrasound vs near‐infrared laser guidance
Pseudoaneurysm · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
no estimate extractedNRNo studies
[Radial] B‐mode ultrasound vs near‐infrared laser guidance
Overall success rate · adults requiring radial artery catheterisation
Ultrasound guidance for arterial (other than femoral) catheterisation in adults (2021) · Cochrane
RR 1.5 [0.27, 8.45]1 study · 72 participantsVery low