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Search review questions
Each row is one question a systematic review asked: who, what, compared with what, and which outcome, with the effect it found and how certain that is. Words match anywhere in the field.
2,112 questions in 171 reviews · Eyes and Vision
current versionsNo studies 587 · 27.8%Ungraded 95 · 4.5%Very low 446 · 21.1%Low 557 · 26.4%Moderate 361 · 17.1%High 66 · 3.1%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
| Question | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Phacoemulsification vs phacoemulsification plus viscogonioplasty Mean IOP change from baseline to 12 months (mmHg) · participants with primary angle‐closure glaucoma Lens extraction for chronic angle‐closure glaucoma (2021) · Cochrane | no estimate extracted | 91 participants | Low |
Intervention NR Disease progression · adults with PACS, PAC or PACG Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Additional medications required · adults with PACS or PAC, and previous PI Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Complications · adults with PACS or PAC, and previous PI Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Further surgical or laser interventions · adults with PACS or PAC, and previous PI Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Quality of life measures · adults with PACS or PAC, and previous PI Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Anterior chamber morphology · adults with PACS or PAC, and previous PI Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | 1 study · 22 participants | Very low |
Intervention NR Disease progressionAssessed by: dilated assessment of the vertical C/D ratio using a 78 D lens · adults with PAC or PACG, and previous PI Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | 1 study · 80 participants | Low |
Intervention NR IOP · adults with PAC or PACG, and previous PI Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | 1 study · 80 participants | Low |
Intervention NR Additional medications required · adults with PAC or PACG, and previous PI Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | 1 study · 80 participants | Low |
Intervention NR Complications · adults with PAC or PACG, and previous PI Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | 1 study · 80 participants | Low |
Intervention NR Further surgical or laser interventions · adults with PAC or PACG, and previous PI Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | 1 study · 80 participants | Low |
Intervention NR IOP · adults with PACS, PAC or PACG Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | 2 studies · 174 participants | Low |
Intervention NR Quality of life measures · adults with PAC or PACG, and previous PI Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Anterior chamber morphology · adults with PAC or PACG, and previous PI Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | 1 study · 80 participants | Very low |
Intervention NR Additional medications required · adults with PACS, PAC or PACG Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | 1 study · 126 participants | Low |
Intervention NR Complications · adults with PACS, PAC or PACG Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | 2 studies · 206 participants | Low |
Intervention NR Further surgical or laser interventions · adults with PACS, PAC or PACG Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | 1 study · 126 participants | Low |
Intervention NR Quality of life measures · adults with PACS, PAC or PACG Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR Anterior chamber morphology · adults with PACS, PAC or PACG Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | 1 study · 48 participants | Low |
Intervention NR Disease progression · adults with PACS or PAC, and previous PI Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | NR | No studies |
Intervention NR IOP · adults with PACS or PAC, and previous PI Laser peripheral iridoplasty for chronic angle closure (2021) · Cochrane | no estimate extracted | 1 study · 22 participants | Very low |
Pneumatic retinopexy vs scleral buckle Reattachment of the retina at 6–12 months · people with simple rhegmatogenous retinal detachments Pneumatic retinopexy versus scleral buckle for repairing simple rhegmatogenous retinal detachments (2021) · Cochrane | RR 0.91 [0.81, 1.02] | NR | Low |
Pneumatic retinopexy vs scleral buckle Recurrence of retinal detachment at 6–12 months · people with simple rhegmatogenous retinal detachments Pneumatic retinopexy versus scleral buckle for repairing simple rhegmatogenous retinal detachments (2021) · Cochrane | RR 1.7 [0.97, 2.98] | NR | Low |
Pneumatic retinopexy vs scleral buckle Mean change in BCVA at 12 months from baseline · people with simple rhegmatogenous retinal detachments Pneumatic retinopexy versus scleral buckle for repairing simple rhegmatogenous retinal detachments (2021) · Cochrane | no estimate extracted | NR | Low |
Pneumatic retinopexy vs scleral buckle Proportion of eyes with final BCVA 20/40 or better at 6 months · people with simple rhegmatogenous retinal detachments Pneumatic retinopexy versus scleral buckle for repairing simple rhegmatogenous retinal detachments (2021) · Cochrane | RR 1.31 [1.04, 1.65] | NR | Low |
Pneumatic retinopexy vs scleral buckle Any operative ocular adverse event at 6–24 months · people with simple rhegmatogenous retinal detachments Pneumatic retinopexy versus scleral buckle for repairing simple rhegmatogenous retinal detachments (2021) · Cochrane | RR 0.55 [0.28, 1.11] | NR | Low |
Pneumatic retinopexy vs scleral buckle Quality of life · people with simple rhegmatogenous retinal detachments Pneumatic retinopexy versus scleral buckle for repairing simple rhegmatogenous retinal detachments (2021) · Cochrane | no estimate extracted | NR | No studies |
Fornix vs limbal‐based conjunctival trabeculectomy flaps Failed trabeculectomy · patients with glaucoma Fornix‐based versus limbal‐based conjunctival trabeculectomy flaps for glaucoma (2021) · Cochrane | no estimate extracted | NR | No studies |
Fornix vs limbal‐based conjunctival trabeculectomy flaps Failed trabeculectomy · patients with glaucoma Fornix‐based versus limbal‐based conjunctival trabeculectomy flaps for glaucoma (2021) · Cochrane | Peto OR 0.36 [0.05, 2.61] | 1 study · 100 participants | Low |
Fornix vs limbal‐based conjunctival trabeculectomy flaps Mean intraocular pressure · patients with glaucoma Fornix‐based versus limbal‐based conjunctival trabeculectomy flaps for glaucoma (2021) · Cochrane | MD 0.86 | 2 studies · 139 participants | Moderate |
Fornix vs limbal‐based conjunctival trabeculectomy flaps Mean intraocular pressure · patients with glaucoma Fornix‐based versus limbal‐based conjunctival trabeculectomy flaps for glaucoma (2021) · Cochrane | MD 0.44 | 4 studies · 247 participants | Moderate |
Fornix vs limbal‐based conjunctival trabeculectomy flaps Visual acuity loss:defined as: loss of visual acuity equal to or greater than 0.3 LogMAR · patients with glaucoma Fornix‐based versus limbal‐based conjunctival trabeculectomy flaps for glaucoma (2021) · Cochrane | no estimate extracted | NR | No studies |
Fornix vs limbal‐based conjunctival trabeculectomy flaps Mean number of medications needed after surgery · patients with glaucoma Fornix‐based versus limbal‐based conjunctival trabeculectomy flaps for glaucoma (2021) · Cochrane | MD 0.02 | 3 studies · 194 participants | High |
Fornix vs limbal‐based conjunctival trabeculectomy flaps Quality of life, assessed by vision‐specific questionnaires · patients with glaucoma Fornix‐based versus limbal‐based conjunctival trabeculectomy flaps for glaucoma (2021) · Cochrane | no estimate extracted | NR | No studies |
Phaco‐AIT vs Phaco‐Trab Proportion of participants who were medication‐free (not using drops) at 12 months · participants 40 to 85 years of age with open‐angle glaucoma Ab interno trabecular bypass surgery with Trabectome for open‐angle glaucoma (2021) · Cochrane | OR 2.33 [0.34, 16.2] | 1 study · 18 participants | Very low |
Phaco‐AIT vs Phaco‐Trab Mean change in IOP (mmHg) at 12 months · participants 40 to 85 years of age with open‐angle glaucoma Ab interno trabecular bypass surgery with Trabectome for open‐angle glaucoma (2021) · Cochrane | no estimate extracted | 1 study · 18 participants | Very low |
Phaco‐AIT vs Phaco‐Trab Mean change in number of IOP‐lowering drops taken per day at 12 months · participants 40 to 85 years of age with open‐angle glaucoma Ab interno trabecular bypass surgery with Trabectome for open‐angle glaucoma (2021) · Cochrane | no estimate extracted | 1 study · 18 participants | Very low |
Phaco‐AIT vs Phaco‐Trab Proportion of participants who required further glaucoma surgery at 12 months · participants 40 to 85 years of age with open‐angle glaucoma Ab interno trabecular bypass surgery with Trabectome for open‐angle glaucoma (2021) · Cochrane | OR 3 | 1 study · 18 participants | Very low |
Phaco‐AIT vs Phaco‐Trab Rate of visual field progression · participants 40 to 85 years of age with open‐angle glaucoma Ab interno trabecular bypass surgery with Trabectome for open‐angle glaucoma (2021) · Cochrane | no estimate extracted | NR | No studies |
Phaco‐AIT vs Phaco‐Trab Mean change in health‐related quality of life · participants 40 to 85 years of age with open‐angle glaucoma Ab interno trabecular bypass surgery with Trabectome for open‐angle glaucoma (2021) · Cochrane | no estimate extracted | NR | No studies |
Phaco‐AIT vs Phaco‐Trab Proportion of participants experiencing intra‐ and postoperative complications · participants 40 to 85 years of age with open‐angle glaucoma Ab interno trabecular bypass surgery with Trabectome for open‐angle glaucoma (2021) · Cochrane | no estimate extracted | 8 participants | Very low |
Sharp‐edged intraocular lens (IOL) vs round‐edged IOL Nd:YAG capsulotomy at one year · people undergoing cataract surgery Intraocular lens optic edge design for the prevention of posterior capsule opacification after cataract… (2021) · Cochrane | OR 0.3 [0.05, 1.74] | 6 studies · 742 participants | Low |
Sharp‐edged intraocular lens (IOL) vs round‐edged IOL Posterior capsule opacification score at one year As measured by AQUA score, Evaluation of PCO (EPCO) score and other methods of quantifying PCO · people undergoing cataract surgery Intraocular lens optic edge design for the prevention of posterior capsule opacification after cataract… (2021) · Cochrane | no estimate extracted | 10 studies · 10 participants | Moderate |
Sharp‐edged intraocular lens (IOL) vs round‐edged IOL BCDVA at one year, measured using logMAR score (range ‐0.3 to 1.3, low scores = better vision, a score of 0 is equivalent to 6/6 or 20/20 vision) · people undergoing cataract surgery Intraocular lens optic edge design for the prevention of posterior capsule opacification after cataract… (2021) · Cochrane | no estimate extracted | 2 studies · 153 participants | Low |
Sharp‐edged intraocular lens (IOL) vs round‐edged IOL Quality of life · people undergoing cataract surgery Intraocular lens optic edge design for the prevention of posterior capsule opacification after cataract… (2021) · Cochrane | no estimate extracted | NR | No studies |
Sharp‐edged intraocular lens (IOL) vs round‐edged IOL Adverse effects · people undergoing cataract surgery Intraocular lens optic edge design for the prevention of posterior capsule opacification after cataract… (2021) · Cochrane | no estimate extracted | NR | Very low |
Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone Proportion of participants who were medication‐free (not using eye‐drops)at 24 months (medium‐term) · people with open‐angle glaucoma Ab interno supraciliary microstent surgery for open‐angle glaucoma (2021) · Cochrane | RR 1.27 [1.09, 1.49] | 1 study · 448 participants | Moderate |
Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone Mean change in unmedicated IOP24 months (medium‐term) · people with open‐angle glaucoma Ab interno supraciliary microstent surgery for open‐angle glaucoma (2021) · Cochrane | no estimate extracted | 1 study · 448 participants | High |
Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone Mean change in daily IOP‐lowering medicationsat 24 months (medium‐term) · people with open‐angle glaucoma Ab interno supraciliary microstent surgery for open‐angle glaucoma (2021) · Cochrane | no estimate extracted | 1 study · 448 participants | Moderate |