Cochrane · systematic review · CD012516

Intraocular lens optic edge design for the prevention of posterior capsule opacification after cataract surgery

Maedel, S, Evans, JR, Harrer-Seely, A, et al. · Cochrane Database of Systematic Reviews · 2021 · Cochrane Library

Eyes and VisionAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
5
current version
GRADE rated
4
No studies
1
Included studies
NR
No studies 1 · 20%Ungraded 0 · 0%Very low 1 · 20%Low 2 · 40%Moderate 1 · 20%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

Sharp‐edged intraocular lens (IOL) compared to round‐edged IOL for the prevention of posterior capsule opacification after cataract surgery

Population: people undergoing cataract surgery
5 questions
OutcomeEffectEvidenceStatus / GRADE
Nd:YAG capsulotomy at one year
Sharp‐edged intraocular lens (IOL) vs round‐edged IOL
OR 0.3 [0.05, 1.74]6 studies · 742 participantsLow
Downgraded: risk of bias, imprecision
Posterior capsule opacification score at one year As measured by AQUA score, Evaluation of PCO (EPCO) score and other methods of quantifying PCO
Sharp‐edged intraocular lens (IOL) vs round‐edged IOL
no estimate extracted10 studies · 10 participantsModerate
Downgraded: risk of bias
BCDVA at one year, measured using logMAR score (range ‐0.3 to 1.3, low scores = better vision, a score of 0 is equivalent to 6/6 or 20/20 vision)
Sharp‐edged intraocular lens (IOL) vs round‐edged IOL
no estimate extracted2 studies · 153 participantsLow
Downgraded: risk of bias, imprecision
Quality of life
Sharp‐edged intraocular lens (IOL) vs round‐edged IOL
no estimate extractedNRNo studies
Adverse effects
Sharp‐edged intraocular lens (IOL) vs round‐edged IOL
no estimate extractedNRVery low
Downgraded: risk of bias, imprecision