Summary of Findings Table ‐ OnabotulinumtoxinA 20U vs placebo
Duration of treatment effect · glabellar lines
1 finding from 1 review
- no estimate extracted1 study · 77 participantsModerate
Findings
What do systematic reviews say?
1,835 questions · 1,886 findings · 74 reviews · Skin
No studies found 542 · 28.7%GRADE not reported 130 · 6.9%Very low 326 · 17.3%Low 434 · 23%Moderate 348 · 18.5%High 106 · 5.6%
Summary of Findings Table ‐ AbobotulinumtoxinA 50U vs placebo
Participant assessment of success by analysing scores and scales ‐ 20 weeks (Validated tools, wrinkles and lines at maximum contraction) · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U leads to higher participant assessment of success by analysing scores and scales ‐… compared with placebo (high certainty).
1 finding from 1 review
- RR 5.33 [1.67, 16.99]1 study · 300 participantsHigh
Summary of Findings Table ‐ AbobotulinumtoxinA 50U vs placebo
Major adverse events (eyelid ptosis, eyelid sensory disorder, strabismus) · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U showed no clear difference in major adverse events (eyelid ptosis, eyelid sensory disorder,… compared with placebo (moderate certainty).
1 finding from 1 review
- RR 3.36 [0.88, 12.87]7 studies · 1294 participantsModerate
Summary of Findings Table ‐ AbobotulinumtoxinA 50U vs placebo
Physician assessment of success · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U probably leads to higher physician assessment of success by analysing scores and scales ‐ 4… compared with placebo (moderate certainty).
1 finding from 1 review
- RR 15.78 [8.75, 28.45]7 studies · 1060 participantsModerate
Summary of Findings Table ‐ AbobotulinumtoxinA 50U vs placebo
Total adverse events · glabellar lines
Summary of Findings Table ‐ AbobotulinumtoxinA 50U may leads to higher total adverse events compared with placebo (low certainty).
1 finding from 1 review
- RR 1.25 [1.05, 1.49]8 studies · 1471 participantsLow
Topical antibiotics vs antiseptic agent
Clinical cure · bacterial folliculitis and boils (furuncles and carbuncles)
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Topical antibiotics vs systemic antibiotics
Minor adverse events not leading to withdrawal of treatment · bacterial folliculitis and boils (furuncles and carbuncles)
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Phototherapy vs sham light
Clinical cure · bacterial folliculitis and boils (furuncles and carbuncles)
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Phototherapy vs sham light
Severe adverse events leading to withdrawal of treatment · bacterial folliculitis and boils (furuncles and carbuncles)
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Phototherapy vs sham light
Quality of life · bacterial folliculitis and boils (furuncles and carbuncles)
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Phototherapy vs sham light
Recurrence of folliculitis or boil following completion of treatment · bacterial folliculitis and boils (furuncles and carbuncles)
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Phototherapy vs sham light
Minor adverse events not leading to withdrawal of treatment · bacterial folliculitis and boils (furuncles and carbuncles)
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Cefadroxil vs flucloxacillin
Clinical cure · bacterial furunculosis
It is very uncertain whether cefadroxil changes clinical cure (measured after 10 days of treatment) compared with flucloxacillin (very low certainty).
1 finding from 1 review
- Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes onlyRR 0.9 [0.7, 1.16]1 study · 41 participantsVery low
Cefadroxil vs flucloxacillin
Severe adverse events leading to withdrawal of treatment · bacterial furunculosis
Cefadroxil showed no clear difference in severe adverse events leading to withdrawal of treatment (reported… compared with flucloxacillin (low certainty).
1 finding from 1 review
- Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes onlyRR 2.97 [0.6, 14.62]1 study · 6514 participantsLow
Cefadroxil vs flucloxacillin
Quality of life · bacterial furunculosis
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Cefadroxil vs flucloxacillin
Recurrence of folliculitis or boil following completion of treatment · bacterial furunculosis
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Topical antibiotics vs antiseptic agent
Severe adverse events leading to withdrawal of treatment · bacterial folliculitis and boils (furuncles and carbuncles)
The review found no eligible studies for this question.
1 finding from 1 review
- Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedNo studies found
Cefadroxil vs flucloxacillin
Minor adverse events not leading to withdrawal of treatment · bacterial furunculosis
Cefadroxil probably leads to lower minor adverse events not leading to withdrawal of treatment… compared with flucloxacillin (moderate certainty).
1 finding from 1 review
- Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes onlyRR 0.78 [0.62, 0.98]1 study · 6514 participantsModerate
Cefdinir vs cefalexin
Clinical cure · bacterial folliculitis and boils (furuncles and carbuncles)
Cefdinir showed no clear difference in clinical cure (measured 17 to 24 days after treatment) compared with cefalexin (low certainty).
1 finding from 1 review
- Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes onlyRR 1 [0.73, 1.38]1 study · 74 participantsLow
Cefdinir vs cefalexin
Severe adverse events leading to withdrawal of treatment · bacterial folliculitis and boils (furuncles and carbuncles)
Cefdinir showed no clear difference in severe adverse events leading to withdrawal of treatment (reported… compared with cefalexin (low certainty).
1 finding from 1 review
- Interventions for bacterial folliculitis and boils (furuncles and carbuncles) 2021 · Cochrane Headline outcomes onlyRR 1.05 [0.07, 16.62]1 study · 3912 participantsLow