Question · asked by 1 review

Cefadroxil vs flucloxacillin: Severe adverse events leading to withdrawal of treatment

Population
bacterial furunculosis
Intervention
Cefadroxil
Comparison
flucloxacillin
Outcome
Severe adverse events leading to withdrawal of treatment

Cefadroxil showed no clear difference in severe adverse events leading to withdrawal of treatment (reported… compared with flucloxacillin (low certainty).

What each review found

Include earlier review versions
FindingEffectStudiesGRADE certainty
Cefadroxil vs flucloxacillin
Severe adverse events leading to withdrawal of treatment (reported during 10 days of treatment) · bacterial furunculosis
Cefadroxil showed no clear difference in severe adverse events leading to withdrawal of treatment (reported… compared with flucloxacillin (low certainty).
Interventions for bacterial folliculitis and boils (furuncles and carbuncles) (2021) · Cochrane Headline outcomes only
RR 2.97 [0.6, 14.62]1 study · 6514 participantsLow

Findings are shown side by side, never pooled across reviews.

The reviews

ReviewSearched up toIncluded studiesAMSTAR 2
Interventions for bacterial folliculitis and boils (furuncles and carbuncles)
2021 · Cochrane Headline outcomes only
Not reportedNot extractedNot assessed
How reviews are matched to this question

Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.