Findings

What do systematic reviews say?

271 questions · 287 findings · 26 reviews · Colorectal

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No studies found 22 · 7.7%GRADE not reported 7 · 2.4%Very low 83 · 28.9%Low 115 · 40.1%Moderate 49 · 17.1%High 11 · 3.8%

Laparoscopic vs open appendectomy

Pain (unpleasantness/intensity/palpation) · patients with suspected appendicitis

1 finding from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 61 participants
Low

Laparoscopic vs open appendectomy

Surgical complications ‐ wound infection · patients with suspected appendicitis

Laparoscopic probably leads to lower wound infections (rate) compared with open appendectomy (moderate certainty).

1 finding from 1 review

Laparoscopic versus open surgery for suspected appendicitis 2018 · Cochrane Headline outcomes only
Peto OR 0.25 [0.15, 0.42]
10 studies · 1245 participants
Moderate

Daikenchuto vs control

Time from completion of operation to first flatus (hours)

1 finding from 1 review

Daikenchuto for reducing postoperative ileus in patients undergoing elective abdominal surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 83 participants
Very low

Daikenchuto vs control

Time from completion of operation to first bowel movement (hours)

1 finding from 1 review

Daikenchuto for reducing postoperative ileus in patients undergoing elective abdominal surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 500 participants
Very low

Daikenchuto vs control

Time from completion of operation to resumption of regular solid food intake (hours)

1 finding from 1 review

Daikenchuto for reducing postoperative ileus in patients undergoing elective abdominal surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 258 participants
Very low

Daikenchuto vs control

Any drug‐related adverse events (CTCAE grade ≥ 2)

Daikenchuto showed no clear difference in any drug‐related adverse events (CTCAE grade ≥ 2) compared with control (low certainty).

1 finding from 1 review

Daikenchuto for reducing postoperative ileus in patients undergoing elective abdominal surgery 2018 · Cochrane Headline outcomes only
RD 0
5 studies · 568 participants
Low

Daikenchuto vs control

Patient satisfaction on day of discharge (Gastrointestinal Symptom Rating Scale (GSRS))

1 finding from 1 review

Daikenchuto for reducing postoperative ileus in patients undergoing elective abdominal surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 81 participants
Very low

Daikenchuto vs control

Incidence ratio of any re‐interventions before leaving hospital

Daikenchuto showed no clear difference in incidence ratio of any re‐interventions before leaving hospital compared with control (moderate certainty).

1 finding from 1 review

Daikenchuto for reducing postoperative ileus in patients undergoing elective abdominal surgery 2018 · Cochrane Headline outcomes only
RR 0.99 [0.06, 15.62]
1 study · 207 participants
Moderate

Daikenchuto vs control

Length of postoperative hospital stay

1 finding from 1 review

Daikenchuto for reducing postoperative ileus in patients undergoing elective abdominal surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 292 participants
Low

Intra‐abdominal drainage vs no drainage after pelvic lymphadenectomy

Anastomotic leakage/dehiscence · unselected population undergoing elective colorectal anastomosis

Intra‐abdominal drainage showed no clear difference in anastomotic dehiscence compared with no drainage (low certainty).

1 finding from 1 review

Intra‐abdominal drains for the prophylaxis of anastomotic leak in elective colorectal surgery 2004 · Cochrane Headline outcomes only
RR 1.4 [0.45, 4.4]
2 studies · 809 participants
Low

Intra‐abdominal drainage vs no drainage after pelvic lymphadenectomy

All‐cause mortality · unselected population undergoing elective colorectal anastomosis

Intra‐abdominal drainage showed no clear difference in mortality compared with no drainage (low certainty).

1 finding from 1 review

Intra‐abdominal drains for the prophylaxis of anastomotic leak in elective colorectal surgery 2004 · Cochrane Headline outcomes only
RR 0.77 [0.41, 1.45]
3 studies · 908 participants
Low