Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

276 questions · 290 findings · 42 reviews · Headline outcomes only

No studies found 26 · 9%GRADE not reported 17 · 5.9%Very low 82 · 28.3%Low 92 · 31.7%Moderate 66 · 22.8%High 7 · 2.4%

Intervention not reported

Discontinuation due to adverse events · Patients with fibromyalgia

It is very uncertain whether the intervention changes discontinuation due to adverse events (very low certainty).

1 finding from 1 review

Intervention not reported

Serious adverse events · Patients with fibromyalgia

It is very uncertain whether the intervention changes serious adverse events (very low certainty).

1 finding from 1 review

Intervention not reported

Low dose SSRI versus placebo Luteal or continuous administration · women with premenstrual syndrome

The intervention probably leads to higher low dose SSRI versus placebo Luteal or continuous administration (moderate certainty).

1 finding from 1 review

Intervention not reported

Mod dose SSRI versus placebo Luteal or continuous administration · women with premenstrual syndrome

The intervention probably leads to higher mod dose SSRI versus placebo Luteal or continuous administration (moderate certainty).

1 finding from 1 review

Intervention not reported

High dose SSRIs versus placebo Continuous administration · women with premenstrual syndrome

The intervention probably leads to higher high dose SSRIs versus placebo Continuous administration (moderate certainty).

1 finding from 1 review