What do systematic reviews say?

Rivastigmine vs placebo

• Rivastigmine for Alzheimer's disease 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 529 participants
  Moderate

Pharmacological agents vs placebo

• Pharmacotherapy for chronic cognitive impairment in traumatic brain injury 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 274 participants
  Very low

Pharmacological agents vs placebo

• Pharmacotherapy for chronic cognitive impairment in traumatic brain injury 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 51 participants
  Low

Pharmacological agents vs placebo

• Pharmacotherapy for chronic cognitive impairment in traumatic brain injury 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 274 participants
  Very low

Pharmacological agents vs placebo

• Pharmacotherapy for chronic cognitive impairment in traumatic brain injury 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 274 participants
  Very low

Pharmacological agents vs placebo

• Pharmacotherapy for chronic cognitive impairment in traumatic brain injury 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 274 participants
  GRADE not reported

Statins vs placebo

• Statins for the treatment of dementia 2014 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1110 participants
  High

Statins vs placebo

• Statins for the treatment of dementia 2014 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 1127 participants
  High

Statins vs placebo

• Statins for the treatment of dementia 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 660 participants
  High

Statins vs placebo

• Statins for the treatment of dementia 2014 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 983 participants
  High

procaine vs placebo

procaine may leads to higher cognitive function improvement in "healthy" elderly persons… compared with placebo (low certainty).

• Procaine treatments for cognition and dementia 2008 · Cochrane Headline outcomes only
  OR 12.71 [3.81, 42.42]
  1 study · 81 participants
  Low

procaine vs placebo

It is very uncertain whether procaine changes cognitive function improvement in demented women Wechsler's memory… compared with placebo (very low certainty).

• Procaine treatments for cognition and dementia 2008 · Cochrane Headline outcomes only
  OR 0.04 [0, 1.12]
  1 study · 12 participants
  Very low

procaine vs placebo

The review found no eligible studies for this question.

• Procaine treatments for cognition and dementia 2008 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

procaine vs placebo

It is very uncertain whether procaine changes overall changes from baseline in demented women compared with placebo (very low certainty).

• Procaine treatments for cognition and dementia 2008 · Cochrane Headline outcomes only
  OR 0.04 [0, 0.83]
  1 study · 12 participants
  Very low

procaine vs placebo

procaine may leads to higher total adverse events in "healthy" persons compared with placebo (low certainty).

• Procaine treatments for cognition and dementia 2008 · Cochrane Headline outcomes only
  OR 7.3 [2.13, 25.02]
  2 studies · 415 participants
  Low