Findings

What do systematic reviews say?

307 questions · 323 findings · 34 reviews

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No studies found 87 · 26.9%GRADE not reported 21 · 6.5%Very low 92 · 28.5%Low 72 · 22.3%Moderate 29 · 9%High 22 · 6.8%

Intervention not reported

Participants with at least 30% or at least 50% reduction in pain · people with cancer pain

1 finding from 1 review

Oral paracetamol (acetaminophen) for cancer pain 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

PGIC much or very much improved · people with cancer pain

1 finding from 1 review

Oral paracetamol (acetaminophen) for cancer pain 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

Mean pain intensity at end of study · people with cancer pain

1 finding from 1 review

Oral paracetamol (acetaminophen) for cancer pain 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 93 participants
Very low

Intervention not reported

Pain no worse than mild at one or two weeks (or equivalent) · people with cancer pain

1 finding from 1 review

Oral paracetamol (acetaminophen) for cancer pain 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Intervention not reported

Mean quality of life or "well‐being" · people with cancer pain

1 finding from 1 review

Oral paracetamol (acetaminophen) for cancer pain 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 93 participants
Very low

Intervention not reported

Participant preference · people with cancer pain

1 finding from 1 review

Oral paracetamol (acetaminophen) for cancer pain 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 52 participants
Very low

Intervention not reported

Adverse events · people with cancer pain

1 finding from 1 review

Oral paracetamol (acetaminophen) for cancer pain 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 80 participants
Very low

Intervention not reported

Serious adverse events · people with cancer pain

1 finding from 1 review

Oral paracetamol (acetaminophen) for cancer pain 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 93 participants
Very low

Intervention not reported

Para/propacetamol vs placebo see footnote1 · patients with postoperative pain

The intervention leads to higher para/propacetamol vs placebo see footnote1 (high certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 2.53 [2.01, 3.19]
11 studies · 1149 participants
High

Intervention not reported

Propacetamol vs placebo see footnote1 · patients with postoperative pain

The intervention may leads to higher propacetamol vs placebo see footnote1 (low certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 2.4 [1.64, 3.5]
6 studies · 611 participants
Low

Intervention not reported

Para/propacetamol vs NSAIDs see footnote1 · patients with postoperative pain

It is very uncertain whether the intervention changes para/propacetamol vs NSAIDs see footnote1 (very low certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 0.79 [0.66, 0.95]
5 studies · 355 participants
Very low

Intervention not reported

Propacetamol vs NSAIDs see footnote1 · patients with postoperative pain

It is very uncertain whether the intervention changes propacetamol vs NSAIDs see footnote1 (very low certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 0.75 [0.56, 1.02]
2 studies · 143 participants
Very low

Intervention not reported

Para/propacetamol vs placebo · patients with postoperative pain

The intervention may leads to lower para/propacetamol vs placebo (low certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 0.7 [0.64, 0.77]
9 studies · 859 participants
Low

Intervention not reported

Propacetamol vs placebo · patients with postoperative pain

The intervention may leads to lower propacetamol vs placebo (low certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 0.49 [0.35, 0.69]
3 studies · 204 participants
Low

Intervention not reported

Para/propacetamol vs NSAIDs · patients with postoperative pain

It is very uncertain whether the intervention changes para/propacetamol vs NSAIDs (very low certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 1.19 [0.87, 1.63]
5 studies · 309 participants
Very low

Intervention not reported

Propacetamol vs NSAIDs · patients with postoperative pain

It is very uncertain whether the intervention changes propacetamol vs NSAIDs (very low certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 1.23 [0.86, 1.77]
3 studies · 189 participants
Very low

Intervention not reported

Propacetamol vs opioids · patients with postoperative pain

It is very uncertain whether the intervention changes propacetamol vs opioids (very low certainty).

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
RR 1.83 [0.72, 4.64]
2 studies · 139 participants
Very low

Intervention not reported

Para/propacetamol vs placebo see footnote1 · patients with postoperative pain

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 777 participants
Moderate

Intervention not reported

Propacetamol vs placebo see footnote1 · patients with postoperative pain

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 373 participants
Low

Intervention not reported

Para/propacetamol vs NSAIDs see footnote1 · patients with postoperative pain

1 finding from 1 review

Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain 2016 · Cochrane Headline outcomes only
no estimate extracted
8 studies · 540 participants
Very low