Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

1,261 questions · 1,287 findings · 210 reviews

No studies found 256 · 19.9%GRADE not reported 123 · 9.6%Very low 248 · 19.3%Low 403 · 31.3%Moderate 208 · 16.2%High 49 · 3.8%

Medical or surgical intervention, or both, for gastro‐oesophageal reflux disease vs nil intervention, delayed intervention control, or placebo

Use of "rescue" medications and emergency action plans: B2 use puffs per day Duration of treatment: range 14 weeks to 24 weeks · treatment for asthma in adults and children with asthma and GORD
1 finding from 1 review

Cilostazol vs pentoxifylline

Adverse event related to study medication ‐ headache (number of cases) · intermittent claudication

Cilostazol may leads to higher adverse event related to study medication ‐ headache (number of cases) compared with pentoxifylline (low certainty).

1 finding from 1 review

Cilostazol vs placebo

Adverse event related to study medication ‐ headache (number of cases) · intermittent claudication

Cilostazol probably leads to higher adverse event related to study medication ‐ headache (number of cases) compared with placebo (moderate certainty).

1 finding from 1 review

Intervention not reported

Additional medications required · adults with PACS or PAC, and previous PI

The review found no eligible studies for this question.

1 finding from 1 review

Discontinuing cholinesterase inhibitor vs continued cholinesterase inhibitor

Dropout due to lack of efficacy of trial medication or deterioration in overall medical condition · people with dementia

Discontinuing cholinesterase inhibitor showed no clear difference in dropout due to lack of efficacy of trial medication or deterioration… compared with continued cholinesterase inhibitor (low certainty).

1 finding from 1 review

Primary health professional‐led or collaborative care vs specialist‐led care

Relapse of severe mental disorder (immediately post intervention) Defined by re‐appearance of symptoms or worsening of symptoms necessitating adjustment of medicationa; Li 2002; based on 1 item scoring ≥ 5 or 2 items scoring ≥ 4 in items 4, 7, 11,... · people with severe mental disorders

It is very uncertain whether primary health professional‐led or collaborative care changes relapse of severe mental disorder (immediately post intervention)… compared with specialist‐led care (very low certainty).

1 finding from 1 review

Phaco‐AIT vs Phaco‐Trab

Proportion of participants who were medication‐free (not using drops) at 12 months · people with open‐angle glaucoma

It is very uncertain whether phaco‐AIT changes proportion of participants who were medication‐free (not using… compared with phaco‐Trab (very low certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Proportion of participants who were medication‐free (not using eye drops) medium‐term · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery probably leads to higher proportion of participants who were medication‐free (not using… compared with phacoemulsification alone (moderate certainty).

1 finding from 1 review

Phacoemulsification + supraciliary microstent surgery vs phacoemulsification alone

Mean change in daily IOP‐lowering medicationsat 24 months (medium‐term) · people with open‐angle glaucoma

Phacoemulsification + supraciliary microstent surgery showed no clear difference in mean change in daily IOP‐lowering medicationsat 24 months… compared with phacoemulsification alone (moderate certainty).

1 finding from 1 review

Nifedipine vs placebo

Requirement for additional medication · primary dysmenorrhoea

It is very uncertain whether nifedipine changes requirement for additional medication compared with placebo (very low certainty).

1 finding from 1 review