Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

2,038 questions · 2,118 findings · 339 reviews

No studies found 323 · 15.3%GRADE not reported 166 · 7.8%Very low 552 · 26.1%Low 592 · 28%Moderate 340 · 16.1%High 145 · 6.8%

CAD/CAM nitinol fixed (bonded) retainer vs Multistrand / spiral wire fixed (bonded) retainer

Adverse effects on oral health: bleeding on probing (lower arch) · People who had received fixed appliance orthodontic treatment

The review found no eligible studies for this question.

1 finding from 1 review

Part-time clear plastic (removable) retainer vs Any type of fixed (bonded) retainer

Patient satisfaction: discomfort/pain (lower arch) · People who had received fixed appliance orthodontic treatment

It is very uncertain whether part-time clear plastic (removable) retainer changes patient satisfaction: discomfort/pain (lower arch) compared with any type of fixed (bonded) retainer (very low certainty).

1 finding from 1 review

Fibre-reinforced composite fixed (bonded) retainer vs Multistrand / spiral wire fixed (bonded) retainer

Survival: mean survival time (lower arch, months) · People who had received fixed appliance orthodontic treatment

The review found no eligible studies for this question.

1 finding from 1 review

Fibre-reinforced composite fixed (bonded) retainer vs Multistrand / spiral wire fixed (bonded) retainer

Stability: Little's Irregularity Index (lower arch) · People who had received fixed appliance orthodontic treatment

It is very uncertain whether fibre-reinforced composite fixed (bonded) retainer changes stability: Little's Irregularity Index (lower arch) compared with multistrand / spiral wire fixed (bonded) retainer (very low certainty).

1 finding from 1 review

CAD/CAM nitinol fixed (bonded) retainer vs Multistrand / spiral wire fixed (bonded) retainer

Stability: Little's Irregularity Index (lower arch) · People who had received fixed appliance orthodontic treatment

It is very uncertain whether CAD/CAM nitinol fixed (bonded) retainer changes stability: Little's Irregularity Index (lower arch) compared with conventional/analogue multistrand fixed (bonded) retainer (very low certainty).

1 finding from 1 review

Full-time wear of removable retainer (any type) vs Part-time wear of removable retainer (any type)

Stability: Little's Irregularity Index (lower arch) · People who had received fixed appliance orthodontic treatment

It is very uncertain whether full-time wear of removable retainer (any type) changes stability: Little's Irregularity Index (lower arch) compared with part-time wear of removable retainer (any type) (very low certainty).

1 finding from 1 review

Full-time clear plastic (removable) retainer vs Any type of fixed (bonded) retainer

Adverse effects on oral health: gingival bleeding (lower arch) · People who had received fixed appliance orthodontic treatment

It is very uncertain whether full-time clear plastic (removable) retainer changes adverse effects on oral health: gingival bleeding (lower arch) compared with any type of fixed (bonded) retainer (very low certainty).

1 finding from 1 review

Full-time clear plastic (removable) retainer vs Any type of fixed (bonded) retainer

Stability: Little's Irregularity Index (lower arch) · People who had received fixed appliance orthodontic treatment

It is very uncertain whether full-time clear plastic (removable) retainer changes stability: Little's Irregularity Index (lower arch) compared with any type of fixed (bonded) retainer (very low certainty).

1 finding from 1 review

Fibre-reinforced composite fixed (bonded) retainer vs Multistrand / spiral wire fixed (bonded) retainer

Adverse effects on oral health: Gingival Index (lower arch) · People who had received fixed appliance orthodontic treatment

The review found no eligible studies for this question.

1 finding from 1 review

Full-time clear plastic (removable) retainer vs Any type of fixed (bonded) retainer

Adverse effects on oral health: caries (lower arch) · People who had received fixed appliance orthodontic treatment

It is very uncertain whether full-time clear plastic (removable) retainer changes adverse effects on oral health: caries (lower arch) compared with any type of fixed (bonded) retainer (very low certainty).

1 finding from 1 review

Intervention not reported

TUG (lower score = faster) · adults following hip fracture surgery

The intervention showed no clear difference in TUG (lower score = faster) (low certainty).

1 finding from 1 review

Intervention not reported

TUG (lower score = faster) · adults following hip fracture surgery

It is very uncertain whether the intervention changes TUG (lower score = faster) (very low certainty).

1 finding from 1 review

Any glucocorticoid vs no glucocorticoids or placebo

Clinical pregnancy rate · assisted reproduction technology cycles

It is very uncertain whether glucocorticoids changes clinical pregnancy rate per couple: dosage and timing of… compared with no glucocorticoids or placebo (very low certainty).

1 finding from 1 review

Interventions (vitamin B1, mefenamic acid, tranexamic acid) vs placebo or active comparators (desmopressin, sodium diclofenac, flavonoids)

Side effects: gastrointestinal disturbances (diarrhoea, lower abdominal pain), headache and sweating

It is very uncertain whether interventions (vitamin B1, mefenamic acid, tranexamic acid) changes side effects: gastrointestinal disturbances (diarrhoea, lower… compared with placebo or active comparators (desmopressin, sodium diclofenac,… (very low certainty).

1 finding from 1 review

Intratympanic corticosteroids vs systemic corticosteroids

Change in hearing threshold determined by PTA Range 0 dB to 140 dB Negative values represent lowering and positive values represent raising of the hearing threshold. A lower hearing threshold represents hearing improvement. Â · sudden sensorineural hearing loss

Intratympanic corticosteroids showed no clear difference in change in hearing threshold determined by PTA Range 0 dB to 140 dB… compared with systemic corticosteroids (low certainty).

1 finding from 1 review